Protein Alignment CG31266 and C1R

DIOPT Version :10

• Sequence 1: NP_001138068.1
• Gene: CG31266 / 42071
• FlyBaseID: FBgn0051266
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_001341275.1
• Gene: C1R / 715
• HGNCID: 1246
• Length: 719
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 78/283 - (27%)
• Similarity: 123/283 - (43%)
• Gaps: 55/283 - (19%)

  Fly    28 RGEPLPGLANIERHRSTEAVPQGRVIGGTTAAEGNWPWIASIQNAYSYH-LCGAIILDETWVLTA 91
            :||.:|....:..........:.|:|||..|..||:||    |...:.| ..|..:|.:.|:|||
Human   454 KGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPW----QVFTNIHGRGGGALLGDRWILTA 514

  Fly    92 ASCVAGLRP--------LNLLVVTGTVDWWDLY-APYYTVSQIHVHCNFDKPLYHN---DIALLQ 144
            |..   |.|        .:|.|..|..:..:|. ...:.:.::.||.::.:...:|   |||||:
Human   515 AHT---LYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLE 576

  Fly   145 LSSKIEFNDVTKNITLADIDELEEGDKLTF-AGWGSSEAMGTYG-RYLQEASGTYLPV---DACR 204
            |.:.:........|.|.|.|...:...:.: :|:|..|....:. |:::      |||   .||.
Human   577 LENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVR------LPVANPQACE 635

  Fly   205 EKLQNQDDVDL--------GHVCVQMDAGQGACHGDTGG------PLIDEQQRLV--GIGNWGVP 253
            ..|:.::.:|:        ||..::.|    ||.||:||      |..|   |.|  ||.:||:.
Human   636 NWLRGKNRMDVFSQNMFCAGHPSLKQD----ACQGDSGGVFAVRDPNTD---RWVATGIVSWGIG 693

  Fly   254 CGRGYPDVYARTAFYHDWIRTTM 276
            |.||| ..|.:...|.|||:..|
Human   694 CSRGY-GFYTKVLNYVDWIKKEM 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31266	NP_001138068.1	Tryp_SPc	52..275	CDD:238113	73/256 (29%)
C1R	NP_001341275.1	CUB	41..152	CDD:214483
		FXa_inhibition	175..203	CDD:464251
		CUB	207..316	CDD:395345
		Sushi	323..385	CDD:459664
		CCP	390..461	CDD:153056	3/6 (50%)
		Tryp_SPc	477..711	CDD:214473	72/254 (28%)