DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31266 and PRSS1

DIOPT Version :9

Sequence 1:	NP_001138068.1	Gene:	CG31266 / 42071	FlyBaseID:	FBgn0051266	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	291	Identity:	74/291 - (25%)
Similarity:	122/291 - (41%)	Gaps:	36/291 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLLGLTLLALQGP---------------TEAMRMRGEPLPGLANIERHRSTEAVPQGRVIGGTTA 58
            ||.|:..|..|.|               ::|......||..|..:....:.......:::||...
Human   191 VLGGVVTLTSQSPPLWILVRYKDESSTTSQAHSTTMNPLLILTFVAAALAAPFDDDDKIVGGYNC 255

  Fly    59 AEGNWPWIASIQNAYSYHLCGAIILDETWVLTAASCVAG-----LRPLNLLVVTGTVDWWDLYAP 118
            .|.:.|:..|:.:  .||.||..:::|.||::|..|...     |...|:.|:.|.       ..
Human   256 EENSVPYQVSLNS--GYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGN-------EQ 311

  Fly   119 YYTVSQIHVHCNFDKPLYHNDIALLQLSSKIEFNDVTKNITLADIDELEEGDKLTFAGWGSSEAM 183
            :...::|..|..:|:...:|||.|::|||:...|.....|:|..... ..|.|...:|||::.:.
Human   312 FINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPP-ATGTKCLISGWGNTASS 375

  Fly   184 GT-YGRYLQEASGTYLPVDACREKLQNQDDVDLGHVCVQ-MDAGQGACHGDTGGPLIDEQQRLVG 246
            |. |...||......|....|......:  :.....||. ::.|:.:|.||:|||::...| |.|
Human   376 GADYPDELQCLDAPVLSQAKCEASYPGK--ITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQ-LQG 437

  Fly   247 IGNWGVPCG-RGYPDVYARTAFYHDWIRTTM 276
            :.:||..|. :..|.||.:...|..||:.|:
Human   438 VVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31266	NP_001138068.1	Tryp_SPc	51..272	CDD:214473	61/228 (27%)
CG31266	NP_001138068.1	Tryp_SPc	52..275	CDD:238113	63/230 (27%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	61/228 (27%)
		Tryp_SPc	249..467	CDD:238113	63/230 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920