DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31266 and C1RL

DIOPT Version :9

Sequence 1:	NP_001138068.1	Gene:	CG31266 / 42071	FlyBaseID:	FBgn0051266	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_057630.2	Gene:	C1RL / 51279	HGNCID:	21265	Length:	487	Species:	Homo sapiens

Alignment Length:	287	Identity:	78/287 - (27%)
Similarity:	121/287 - (42%)	Gaps:	59/287 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EAMRMRGEPLPGLANIERHRSTEAVPQGRVIGGTTAAEGNWPWIASIQNAYSYH-LCGAIILDET 86
            :.|.:.|.|:..:|   ::::|        :|.:.|..||:||    |...|.| ..|..:|.:.
Human   227 QCMPVCGRPVTPIA---QNQTT--------LGSSRAKLGNFPW----QAFTSIHGRGGGALLGDR 276

  Fly    87 WVLTAASCV-----AGLR---PLNLLVVTGTVDWWDLYAPYYTVSQIHVHCNFDKPLYHN---DI 140
            |:||||..:     ..||   .:|:.:....:|.. |....:.|.::.||.::.:...||   ||
Human   277 WILTAAHTIYPKDSVSLRKNQSVNVFLGHTAIDEM-LKLGNHPVHRVVVHPDYRQNESHNFSGDI 340

  Fly   141 ALLQLSSKIEFNDVTKNITLADIDELEEGDKLTFA-------GWGSSEAMGTYGRYLQEASGTYL 198
            |||:|...|........:.|.|.:.|.....|.:.       ||.::|.  .|.|         |
Human   341 ALLELQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFGMEMGWLTTEL--KYSR---------L 394

  Fly   199 PV---DACREKLQNQDDVDL---GHVCVQMDAGQ-GACHGDTGGPLI--DEQQR---LVGIGNWG 251
            ||   :||...||.:...::   ...||..:..: ..|.||:|...:  |....   ..||.:||
Human   395 PVAPREACNAWLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWG 459

  Fly   252 VPCGRGYPDVYARTAFYHDWIRTTMNG 278
            :.||.|| |.|.:...|.|||:..|||
Human   460 IGCGEGY-DFYTKVLSYVDWIKGVMNG 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31266	NP_001138068.1	Tryp_SPc	51..272	CDD:214473	68/251 (27%)
CG31266	NP_001138068.1	Tryp_SPc	52..275	CDD:238113	70/253 (28%)
C1RL	NP_057630.2	CUB	40..162	CDD:238001
		Tryp_SPc	247..480	CDD:238113	69/249 (28%)
		Tryp_SPc	247..479	CDD:214473	68/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141692
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930