DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31266 and C1r

DIOPT Version :9

Sequence 1:	NP_001138068.1	Gene:	CG31266 / 42071	FlyBaseID:	FBgn0051266	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_001128027.1	Gene:	C1r / 312705	RGDID:	1309091	Length:	707	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	74/308 - (24%)
Similarity:	131/308 - (42%)	Gaps:	69/308 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLALQGPTEAMR--------------MRGEPLPGLANIERHRSTEAVPQGRVIGGTTAAEGNWPW 65
            ::...|.:|::|              ..||.:|....:..........:.|:|||..|..||:||
  Rat   413 MMTRAGSSESVRGIYTCTPQGIWKNEEEGEKMPRCLPVCGKPVNPVTQKQRIIGGQKANPGNFPW 477

  Fly    66 IASIQNAYSYHLCGAIILDETWVLTAASCV---AGLRPLNLLVVTGTVDWWDLYAPYYTVSQIH- 126
            .| ..|.:...  |..:|.:.|:||||..:   ...:..|:.|..      |::..:..|.:|.
  Rat   478 QA-FTNIHGRG--GGALLGDRWILTAAHTIYPKEHNKENNVNVSK------DVFLGHTNVEEIKK 533

  Fly   127 ----------VHCNF--DKP-LYHNDIALLQLSSKIEFNDVTKNITLADIDELEEGDKLTF-AGW 177
                      :|.::  |:| .:..|||||:|.:.:........|.|.|.:...:.|.:.: :|:
  Rat   534 LGHHPVRRVIIHPDYRQDEPNNFEGDIALLELENSVTLGPNLLPICLPDNETFYDKDLMGYVSGF 598

  Fly   178 GSSEAMGTYG-RYLQEASGTYLPV---DACREKLQNQDDVDL--------GHVCVQMDAGQGACH 230
            |.:|....:. |:::      ||:   :||:..|:.::..|:        |...::.|    ||.
  Rat   599 GITEDKIAFNLRFVR------LPIADREACQRWLRTKNSNDVFSQNMFCSGDPTLKHD----ACQ 653

  Fly   231 GDTGGPL-IDEQQR----LVGIGNWGVPCGRGYPDVYARTAFYHDWIR 273
            ||:||.. :.::.|    ..||.:||:.||.|| ..|.:...|.|||:
  Rat   654 GDSGGVFAVRDRSRDIWVATGIVSWGIGCGEGY-GFYTKLLNYVDWIK 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31266	NP_001138068.1	Tryp_SPc	51..272	CDD:214473	66/255 (26%)
CG31266	NP_001138068.1	Tryp_SPc	52..275	CDD:238113	67/257 (26%)
C1r	NP_001128027.1	CUB	27..138	CDD:214483
		FXa_inhibition	161..189	CDD:291342
		CUB	195..302	CDD:278839
		Sushi	309..371	CDD:278512
		Sushi	376..447	CDD:278512	6/33 (18%)
		Tryp_SPc	463..699	CDD:214473	66/255 (26%)
		Tryp_SPc	464..701	CDD:238113	67/257 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335389
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930