Protein Alignment CG4053 and KLK4

DIOPT Version :9

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 77/260 - (29%)
• Similarity: 137/260 - (52%)
• Gaps: 38/260 - (14%)

  Fly    11 LLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHI-CSGVILNEQWILTA 74
            |:||.:..:..|.        .::|:.|::......|:|.::  :.:..: ||||:::.||:|:|
Human    15 LILGVAGSLVSGS--------CSQIINGEDCSPHSQPWQAAL--VMENELFCSGVLVHPQWVLSA 69

  Fly    75 GHC-----ALDFSIEDLRIIVGTNDRLEPGQTLFPDEALV-HCLYDIPYVYNNDIALIHVNESII 133
            .||     .:...:..|..     |: |||..:......| |..|:.| :..||:.||.::||:.
Human    70 AHCFQNSYTIGLGLHSLEA-----DQ-EPGSQMVEASLSVRHPEYNRP-LLANDLMLIKLDESVS 127

  Fly   134 FNDRTQIVELSREQPPAGSTVTLTGWG-APESSYPTVQYLQTLNLTIIAHEECRERWDFHDGIDI 197
            .:|..:.:.::.:.|.||::..::||| ......|||  ||.:|:::::.|.|.:.:|     .:
Human   128 ESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTV--LQCVNVSVVSEEVCSKLYD-----PL 185

  Fly   198 GHICTFTREG----EGACSGDSGGPLMWEGKLVGLVNWGRA-CG-VGMPDMYANTVYYQDWIRRT 256
            .|...|...|    :.:|:|||||||:..|.|.|||::|:| || ||:|.:|.|...:.:||.:|
Human   186 YHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKT 250

  Fly   257  256
            Human   251  250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	70/232 (30%)
		Tryp_SPc	35..256	CDD:238113	72/234 (31%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	72/234 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850