Protein Alignment CG4053 and TPSAB1

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 74/255 - (29%)
• Similarity: 107/255 - (41%)
• Gaps: 54/255 - (21%)

  Fly    35 IVGGQEAEDGVAPYQVSIQT---IWKTHICSGVILNEQWILTAGHCALDFSIEDLRIIVGTNDRL 96
            |||||||.....|:|||::.   .| .|.|.|.:::.||:|||.||.    ..|::.:.....:|
Human    31 IVGGQEAPRSKWPWQVSLRVHGPYW-MHFCGGSLIHPQWVLTAAHCV----GPDVKDLAALRVQL 90

  Fly    97 EPGQTLFPDEAL------VHCLYDIPYVY----NNDIALIHVNESIIFNDRTQIVELSREQPPAG 151
            ......:.|:.|      ||     |..|    ..||||:.:.|.:..:.....|.|    |||.
Human    91 REQHLYYQDQLLPVSRIIVH-----PQFYTAQIGADIALLELEEPVNVSSHVHTVTL----PPAS 146

  Fly   152 STVT------LTGWGAPESS--YPTVQYLQTLNLTIIAHEECRERWDFHDGIDIGHICTFTREG- 207
            .|..      :||||..::.  .|....|:.:.:.|:.:..|..:  :|.|...|......|:.
Human   147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAK--YHLGAYTGDDVRIVRDDM 209

  Fly   208 -------EGACSGDSGGPLM------WEGKLVGLVNWGRACG-VGMPDMYANTVYYQDWI 253
                   ..:|.|||||||:      |  ...|:|:||..|. ...|.:|....||.|||
Human   210 LCAGNTRRDSCQGDSGGPLVCKVNGTW--LQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	74/255 (29%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	74/255 (29%)