DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4053 and KLK7

DIOPT Version :9

Sequence 1:NP_650601.2 Gene:CG4053 / 42070 FlyBaseID:FBgn0038482 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_005037.1 Gene:KLK7 / 5650 HGNCID:6368 Length:253 Species:Homo sapiens


Alignment Length:267 Identity:80/267 - (29%)
Similarity:141/267 - (52%) Gaps:30/267 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAVRLSL-IWLLLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGV 64
            ||..|.| :.:|||..::: |.|:.....|::|     |.....|..|:||::.:..:.| |.||
Human     1 MARSLLLPLQILLLSLALE-TAGEEAQGDKIID-----GAPCARGSHPWQVALLSGNQLH-CGGV 58

  Fly    65 ILNEQWILTAGHCALDFSIEDLRIIVGTN---DRLEPGQTLFPDEALVHCLYDIPYVYNNDIALI 126
            ::||:|:|||.||.::    :..:.:|::   ||  ..|.:...::..|..|. ...:.||:.|:
Human    59 LVNERWVLTAAHCKMN----EYTVHLGSDTLGDR--RAQRIKASKSFRHPGYS-TQTHVNDLMLV 116

  Fly   127 HVNESIIFNDRTQIVEL-SREQPPAGSTVTLTGWG---APESSYPTVQYLQTLNLTIIAHEECRE 187
            .:|.....:...:.|.| ||.:|| |:|.|::|||   :|:.::|:  .|..:::.:|:.::|.:
Human   117 KLNSQARLSSMVKKVRLPSRCEPP-GTTCTVSGWGTTTSPDVTFPS--DLMCVDVKLISPQDCTK 178

  Fly   188 RWDFHDGIDIGHICTFTREG-EGACSGDSGGPLMWEGKLVGLVNWGR-ACG-VGMPDMYANTVYY 249
              .:.|.::...:|....:. :.||:|||||||:..|.|.|||:||. .|| ...|.:|.....:
Human   179 --VYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKF 241

  Fly   250 QDWIRRT 256
            ..||..|
Human   242 TKWINDT 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4053NP_650601.2 Tryp_SPc 34..253 CDD:214473 66/228 (29%)
Tryp_SPc 35..256 CDD:238113 68/230 (30%)
KLK7NP_005037.1 Tryp_SPc 29..245 CDD:214473 68/233 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165147494
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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