DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4053 and PRSS2

DIOPT Version :9

Sequence 1:NP_650601.2 Gene:CG4053 / 42070 FlyBaseID:FBgn0038482 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_001290343.1 Gene:PRSS2 / 5645 HGNCID:9483 Length:261 Species:Homo sapiens


Alignment Length:265 Identity:82/265 - (30%)
Similarity:130/265 - (49%) Gaps:29/265 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LLLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTA 74
            |||:.|.:........|:    |::||||...|:...|||||:.:.:  |.|.|.:::|||:::|
Human     3 LLLILTFVAAAVAAPFDD----DDKIVGGYICEENSVPYQVSLNSGY--HFCGGSLISEQWVVSA 61

  Fly    75 GHC---ALDFSIED-------LRIIVGT-NDRLEPGQTLFPDEALV--HCLYDIPYVYNNDIALI 126
            |||   |::..:..       :::.:|. |..:..|...|.:.|.:  |..|: ....:|||.||
Human    62 GHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYN-SRTLDNDILLI 125

  Fly   127 HVNESIIFNDRTQIVELSREQPPAGSTVTLTGWGAPESS---YPTVQYLQTLNLTIIAHEECRER 188
            .::...:.|.|...:.|....|.||:...::|||...||   ||  ..||.|:..:::..||.. 
Human   126 KLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYP--DELQCLDAPVLSQAECEA- 187

  Fly   189 WDFHDGIDIGHICT-FTREGEGACSGDSGGPLMWEGKLVGLVNWGRACG-VGMPDMYANTVYYQD 251
             .:...|.....|. |...|:.:|.||||||::..|:|.|:|:||..|. ...|.:|.....|.|
Human   188 -SYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVD 251

  Fly   252 WIRRT 256
            ||:.|
Human   252 WIKDT 256

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4053NP_650601.2 Tryp_SPc 34..253 CDD:214473 73/236 (31%)
Tryp_SPc 35..256 CDD:238113 75/238 (32%)
PRSS2NP_001290343.1 Tryp_SPc 23..253 CDD:214473 73/236 (31%)
Tryp_SPc 24..256 CDD:238113 75/238 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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