Protein Alignment CG4053 and PRSS1

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 80/254 - (31%)
• Similarity: 123/254 - (48%)
• Gaps: 23/254 - (9%)

  Fly    11 LLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTAG 75
            ||:.|.:........|:    |::||||...|:...|||||:.:.:  |.|.|.::||||:::||
Human     4 LLILTFVAAALAAPFDD----DDKIVGGYNCEENSVPYQVSLNSGY--HFCGGSLINEQWVVSAG 62

  Fly    76 HCALDFSIEDLRIIVGT-NDRLEPGQTLFPDEALV--HCLYDIPYVYNNDIALIHVNESIIFNDR 137
            ||..    ..:::.:|. |..:..|...|.:.|.:  |..|| ....||||.||.::...:.|.|
Human    63 HCYK----SRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYD-RKTLNNDIMLIKLSSRAVINAR 122

  Fly   138 TQIVELSREQPPAGSTVTLTGWGAPESS---YPTVQYLQTLNLTIIAHEECRERWDFHDGIDIGH 199
            ...:.|....|..|:...::|||...||   ||  ..||.|:..:::..:|..  .:...|....
Human   123 VSTISLPTAPPATGTKCLISGWGNTASSGADYP--DELQCLDAPVLSQAKCEA--SYPGKITSNM 183

  Fly   200 ICT-FTREGEGACSGDSGGPLMWEGKLVGLVNWGRACG-VGMPDMYANTVYYQDWIRRT 256
            .|. |...|:.:|.||||||::..|:|.|:|:||..|. ...|.:|.....|..||:.|
Human   184 FCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNT 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	74/228 (32%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	72/226 (32%)