Protein Alignment CG4053 and KLK15

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 74/268 - (27%)
• Similarity: 117/268 - (43%)
• Gaps: 35/268 - (13%)

  Fly     8 IWLLL-LGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWI 71
            :|||| |...:..|..:  |..|||:     |.|......|:||::....:.: |...:::..|:
Human     1 MWLLLTLSFLLASTAAQ--DGDKLLE-----GDECAPHSQPWQVALYERGRFN-CGASLISPHWV 57

  Fly    72 LTAGHCALDFSIEDLRIIVGTND---RLEPGQTLFPDEALVHCLYDIPYVYNNDIALIHVNESII 133
            |:|.||...|    :|:.:|.::   |..|.|.......:.|..|: ...:.|||.|:.:.:...
Human    58 LSAAHCQSRF----MRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE-ARSHRNDIMLLRLVQPAR 117

  Fly   134 FNDRTQIVELSREQPPAGSTVTLTGW-----------GAPESSYPTVQYLQTLNLTIIAHEECRE 187
            .|.:.:...|....|..|....::||           |:|.|.......|...|::||:...|.:
Human   118 LNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDK 182

  Fly   188 RWDFHDGIDIGHICTFTREGEGA--CSGDSGGPLMWEGKLVGLVNWGRA-C-GVGMPDMYANTVY 248
              .:...:....:|. ..||.||  |.|||||||:..|.|.|:|:||.. | ....|.:|....:
Human   183 --SYPGRLTNTMVCA-GAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCH 244

  Fly   249 YQDWIRRT 256
            |.:|||.|
Human   245 YLEWIRET 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	63/238 (26%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	60/232 (26%)