Protein Alignment CG4053 and PLG

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 73/254 - (28%)
• Similarity: 115/254 - (45%)
• Gaps: 40/254 - (15%)

  Fly    22 GKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTAGHCALDFS--IE 84
            ||.....|....|:|||..|.....|:|||::|.:..|.|.|.:::.:|:|||.|| |:.|  ..
Human   568 GKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHC-LEKSPRPS 631

  Fly    85 DLRIIVGTND--RLEPGQTLFPDEALVHCLYDIPYVYNNDIALIHVNESIIFNDRTQIVELSREQ 147
            ..::|:|.:.  .|||    ...|..|..|:..|  ...||||:.::...:..|:.....|
Human   632 SYKVILGAHQEVNLEP----HVQEIEVSRLFLEP--TRKDIALLKLSSPAVITDKVIPACL---- 686

  Fly   148 PPAGSTVT-------LTGWGAPESSYPTVQYLQTLNLTIIAHEECRERWDFHDG------IDIGH 199
             |:.:.|.       :||||..:.:: ....|:...|.:|.::.| .|::|.:|      :..||
Human   687 -PSPNYVVADRTECFITGWGETQGTF-GAGLLKEAQLPVIENKVC-NRYEFLNGRVQSTELCAGH 748

  Fly   200 ICTFTREGEGACSGDSGGPLMWEGK----LVGLVNWGRACG-VGMPDMYANTVYYQDWI 253
            :.    .|..:|.|||||||:...|    |.|:.:||..|. ...|.:|.....:..||
Human   749 LA----GGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWI 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	69/241 (29%)
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527
		Tryp_SPc	581..804	CDD:238113	69/241 (29%)