Protein Alignment CG4053 and ACR

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 74/277 - (26%)
• Similarity: 116/277 - (41%)
• Gaps: 34/277 - (12%)

  Fly    10 LLLLGTSI--------DVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTI----WKTHICS 62
            ||:|..|:        |...|.|.........|||||:.|:.|..|:.||:|..    .:.|.|.
Human    10 LLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCG 74

  Fly    63 GVILNEQWILTAGHCAL-DFSIEDLRIIVGTNDRL--------EPGQTLFPDEALVHCLYDIPYV 118
            |.:||.:|:|||.||.: ..::.|.|::.|..:..        .|.|..:.::.::|..|: ...
Human    75 GSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYN-SAT 138

  Fly   119 YNNDIALIHVNESII---FNDRTQIVELSREQPPAGSTVTLTGWGAPESSYP-TVQYLQTLNLTI 179
            ..|||||:.:...|.   |.....:.......|....:..:.|||..|...| ....|....:.:
Human   139 EGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDL 203

  Fly   180 IAHEECRERWDFHDGIDIGHICTFTREGE-GACSGDSGGPLMWEGK------LVGLVNWGRACG- 236
            |..:.|.....::..:...::|.....|: ..|.||||||||.:..      :||:.:||..|.
Human   204 IDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCAR 268

  Fly   237 VGMPDMYANTVYYQDWI 253
            ...|.:|..|..|.:||
Human   269 AKRPGIYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	66/244 (27%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	65/243 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421