Protein Alignment CG4053 and KLK12

DIOPT Version :9

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 74/264 - (28%)
• Similarity: 116/264 - (43%)
• Gaps: 60/264 - (22%)

  Fly     5 LSLIWLL-LLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHI-CSGVILN 67
            ||:..|| :||.|...|            .:|..|.|......|:||.:  ...|.: |.||:::
Human     3 LSIFLLLCVLGLSQAAT------------PKIFNGTECGRNSQPWQVGL--FEGTSLRCGGVLID 53

  Fly    68 EQWILTAGHCALDFSIEDLRIIVGTNDRLEPGQ----TLFPDEALVHCLYDIPY--------VYN 120
            .:|:|||.||:            |:...:..|:    .|...|.:.|..:.:.:        .:.
Human    54 HRWVLTAAHCS------------GSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHE 106

  Fly   121 NDIALIHVNESIIFNDRTQIVELSREQPPAGSTVTLTGWGA---PESSYPTVQYLQTLNLTIIAH 182
            :|:.|:.:...:......|.:.|..:...||:...::|||.   |.:.:|.:  ||.|||:|::|
Human   107 HDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDL--LQCLNLSIVSH 169

  Fly   183 EECRERWDFHDGIDIGHI-----CTFTREGEGACSGDSGGPLMWEGKLVGLVNWGRA--CGV-GM 239
            ..|.       |:..|.|     |.....|:.||.|||||||:..|.|.|||:||..  ||. |:
Human   170 ATCH-------GVYPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGI 227

  Fly   240 PDMY 243
            |.:|
Human   228 PGVY 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	66/234 (28%)
		Tryp_SPc	35..256	CDD:238113	66/233 (28%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	66/234 (28%)
		Tryp_SPc	22..236	CDD:238113	66/233 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920