Protein Alignment CG4053 and KLK2

DIOPT Version :9

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 73/266 - (27%)
• Similarity: 136/266 - (51%)
• Gaps: 27/266 - (10%)

  Fly     8 IWLLLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWIL 72
            :|.|:|..::.|.....:   .|:.:|||||.|.|....|:||::.:....| |.||:::.||:|
Human     1 MWDLVLSIALSVGCTGAV---PLIQSRIVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQWVL 61

  Fly    73 TAGHCALDFSIEDLRIIVGTNDRLEP---GQTLFPDEALVHCLYDIPYV----------YNNDIA 124
            ||.||..    ::.::.:|.::..||   ||.:....:..|.||::..:          .::|:.
Human    62 TAAHCLK----KNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLM 122

  Fly   125 LIHVNESIIFNDRTQIVELSREQPPAGSTVTLTGWGAPE-SSYPTVQYLQTLNLTIIAHEECRER 188
            |:.::|.....|..:::.|..::|..|:|...:|||:.| ..:...:.||.::|.:::::.|...
Human   123 LLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA 187

  Fly   189 WDFHDGIDIGHICT-FTREGEGACSGDSGGPLMWEGKLVGLVNWG-RACGV-GMPDMYANTVYYQ 250
              :.:.:....:|. ....|:..|.|||||||:..|.|.|:.:|| ..|.: ..|.:|...|:|:
Human   188 --YSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250

  Fly   251 DWIRRT 256
            .||:.|
Human   251 KWIKDT 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	65/235 (28%)
		Tryp_SPc	35..256	CDD:238113	66/237 (28%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	66/237 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840