Protein Alignment CG4053 and KLK1

DIOPT Version :9

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 82/258 - (31%)
• Similarity: 125/258 - (48%)
• Gaps: 53/258 - (20%)

  Fly    31 LDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTAGHCALDFSIEDLRIIVGTNDR 95
            :.:|||||.|.|....|:|.::.. :.|..|.|::::.||:|||.||..|            |.:
Human    21 IQSRIVGGWECEQHSQPWQAALYH-FSTFQCGGILVHRQWVLTAAHCISD------------NYQ 72

  Fly    96 LEPGQ-TLFPDE---ALVHCLYDIPYV-----------------YNNDIALIHVNE-SIIFNDRT 138
            |..|: .||.||   ..||.....|:.                 |::|:.|:.:.| :....|..
Human    73 LWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAV 137

  Fly   139 QIVELSREQPPAGSTVTLTGWGA--PES-SYPTVQYLQTLNLTIIAHEECRER-----WDFHDGI 195
            ::|||..|:|..|||...:|||:  ||: |:|  ..||.::|.|:.::||::.     .||.  :
Human   138 KVVELPTEEPEVGSTCLASGWGSIEPENFSFP--DDLQCVDLKILPNDECKKAHVQKVTDFM--L 198

  Fly   196 DIGHICTFTREGEGACSGDSGGPLMWEGKLVGLVNWGRA-CGV-GMPDMYANTVYYQDWIRRT 256
            .:||:    ..|:..|.||||||||.:|.|.|:.:||.. ||. ..|.:....:.|..||..|
Human   199 CVGHL----EGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDT 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	79/250 (32%)
		Tryp_SPc	35..256	CDD:238113	80/252 (32%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	80/252 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147492
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840