DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4053 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_650601.2	Gene:	CG4053 / 42070	FlyBaseID:	FBgn0038482	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	75/248 - (30%)
Similarity:	108/248 - (43%)	Gaps:	38/248 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTAGHCALDF-SIEDLRIIVG 91
            :.|...|:|||.||.....|:||||| ..|.|:|.|.||:..|||||.||...: .:...::..|
  Rat   239 KSLKTTRVVGGVEASADSWPWQVSIQ-YNKQHVCGGSILDHHWILTAAHCFRKYLDVSSWKVRAG 302

  Fly    92 TNDR-------------LEPGQTLFPDEALVHCLYDIPYVYNNDIALIHVNESIIFND--RTQIV 141
            :|..             .|| ..|.|.|              .||||:.:...:.|:.  |...:
  Rat   303 SNKLGNSPSLPVAKIFIAEP-NPLQPKE--------------KDIALVKLKMPLTFSGSVRPICL 352

  Fly   142 ELSREQPPAGSTVTLTGWG-APESSYPTVQYLQTLNLTIIAHEECRERWDFHDGIDIGHICTFTR 205
            ..|.|:......|.:.||| ..|:.......|...::.:|....|.....:...:..|.:|..|.
  Rat   353 PFSDEELIPTMPVWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGMLCAGTP 417

  Fly   206 E-GEGACSGDSGGPLMW---EGKLVGLVNWGRACG-VGMPDMYANTVYYQDWI 253
            : |:..|.||||||||:   :.::||:|:||..|| ...|.:|.....|.|||
  Rat   418 QGGKDTCQGDSGGPLMYHYDKWQVVGIVSWGYGCGSPSTPGVYTKVTAYLDWI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	72/240 (30%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	73/241 (30%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346
		Tryp_SPc	245..470	CDD:214473	72/240 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341254
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840