Protein Alignment CG4053 and PRSS41

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001382429.1
• Gene: PRSS41 / 360226
• HGNCID: 30715
• Length: 334
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 76/278 - (27%)
• Similarity: 118/278 - (42%)
• Gaps: 75/278 - (26%)

  Fly    35 IVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTAGHC------ALDFSIE--------- 84
            :.||.|:..|..|:|.|:: :.:.|.|.|.:|:.:|:|:|.||      ..:::::
Human    71 VAGGVESARGRWPWQASLR-LRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPT 134

  Fly    85 --DLRIIVGTNDRLEPGQTLFPDEALVHCLYDIPYVYNNDIALIHVNESIIFNDRTQIVELSREQ 147
              :||   ..:.|.:....:...:||        .|..|||||:.:..|:.:|...|.:.:.
Human   135 PWNLR---AYSSRYKVQDIIVNPDAL--------GVLRNDIALLRLASSVTYNAYIQPICIE--- 185

  Fly   148 PPAGSTVT--------LTGWG--APESS-YPTVQYLQTLNLTIIAHEECR---ER-------WD- 190
               .||..        :||||  :|..: .|....|:...:||:.:..|.   |:       ||
Human   186 ---SSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDS 247

  Fly   191 -FHDGIDIGHICTFTREGEGACSGDSGGPL------MWEGKLVGLVNWGRACG-VGMPDMYANTV 247
             |..|.:.|.:.|        |.|||||||      :|  ..||:|:||..|| ...|.:|.|..
Human   248 MFCAGAEDGSVDT--------CKGDSGGPLVCDKDGLW--YQVGIVSWGMDCGQPNRPGVYTNIS 302

  Fly   248 YYQDWIRRTHSGCKNRVN 265
            .|..||||..|....|.|
Human   303 VYFHWIRRVMSHSTPRPN 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	72/267 (27%)
PRSS41	NP_001382429.1	Tryp_SPc	71..311	CDD:238113	72/267 (27%)