DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4053 and CG30091

DIOPT Version :9

Sequence 1:	NP_650601.2	Gene:	CG4053 / 42070	FlyBaseID:	FBgn0038482	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	73/287 - (25%)
Similarity:	120/287 - (41%)	Gaps:	56/287 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 WLLLLGTSIDVTRGKRLDNRKLLDN----------RIVGGQEAEDGVAPYQVSIQTIWKTHICSG 63
            |::|....:...||    :.:|||.          :||||.:|.:...|:...|:|. ...||.|
  Fly     5 WVVLFAWMLTAGRG----SARLLDEDCGVPMQLIPKIVGGVDAGELKNPWMALIKTN-DEFICGG 64

  Fly    64 VILNEQWILTAGHCALD-----FSIEDLRIIVGTNDRLEPGQTLFPDEALVHCLYDIPYV----- 118
            .::..:::|||.||...     .....|.:.:|....|..|:...|     |.:|::..|
  Fly    65 SVITNKFVLTAAHCMCTDEECIVKYTQLTVTLGVYHLLATGEHNHP-----HEIYNVERVYIHDS 124

  Fly   119 -----YNNDIALIHVNESIIFNDRTQ--IVELSREQPPAGSTV---TLTGWGAPESSYPTVQYLQ 173
                 |.|||||:.:.:||::..:.:  .:.|:.:..|....:   |..|||...:...: ..||
  Fly   125 FAIQNYRNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMS-NNLQ 188

  Fly   174 TLNLTIIAHEECRERWDFHDGIDIGHICTFTREGEGACSGDSGGPL----MWEG----KLVGLVN 230
            .:.:..|..:.|...  |....|....|..|..|...|..||||||    :::|    ..:|:|:
  Fly   189 MVKIYRIDRKMCEAA--FWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVS 251

  Fly   231 WG-RAC-GVGMPDMYANTVYYQDWIRR 255
            .| ..| |.|   ||.:.:.:.|:|.|
  Fly   252 TGTEDCRGFG---MYTDVMGHIDFIER 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	64/248 (26%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	66/251 (26%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	64/248 (26%)
		Tryp_SPc	37..276	CDD:238113	66/251 (26%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010