DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4053 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_650601.2	Gene:	CG4053 / 42070	FlyBaseID:	FBgn0038482	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_663378.1	Gene:	Tmprss4 / 214523	MGIID:	2384877	Length:	435	Species:	Mus musculus

Alignment Length:	272	Identity:	83/272 - (30%)
Similarity:	116/272 - (42%)	Gaps:	51/272 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IDVTRGKR------------LD-NRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNE 68
            :.|..|.|            || .:.|...|:|||.||.....|:||||| ..|.|:|.|.||:.
Mouse   172 LQVQNGSRSCLSGSLVSLRCLDCGKSLKTPRVVGGVEAPVDSWPWQVSIQ-YNKQHVCGGSILDP 235

  Fly    69 QWILTAGHC---ALDFSIEDLRI---IVGTNDRL--------EPGQTLFPDEALVHCLYDIPYVY 119
            .|||||.||   .||.|...:|.   |:|.:..|        || ..|:|.|
Mouse   236 HWILTAAHCFRKYLDVSSWKVRAGSNILGNSPSLPVAKIFIAEP-NPLYPKE------------- 286

  Fly   120 NNDIALIHVNESIIFND--RTQIVELSREQPPAGSTVTLTGWG-APESSYPTVQYLQTLNLTIIA 181
             .||||:.:...:.|:.  |...:..|.|.....:.|.:.||| ..|:.......|...::.:|.
Mouse   287 -KDIALVKLQMPLTFSGSVRPICLPFSDEVLVPATPVWVIGWGFTEENGGKMSDMLLQASVQVID 350

  Fly   182 HEECRERWDFHDGIDIGHICTFTRE-GEGACSGDSGGPLMWEG---KLVGLVNWGRAC-GVGMPD 241
            ...|.....:...:....:|..|.: |:..|.||||||||:..   ::||:|:||..| |...|.
Mouse   351 STRCNAEDAYEGEVTAEMLCAGTPQGGKDTCQGDSGGPLMYHSDKWQVVGIVSWGHGCGGPSTPG 415

  Fly   242 MYANTVYYQDWI 253
            :|.....|.:||
Mouse   416 VYTKVTAYLNWI 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	75/240 (31%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	76/241 (32%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:295335	5/22 (23%)
		Tryp_SPc	202..427	CDD:214473	75/240 (31%)
		Tryp_SPc	203..430	CDD:238113	76/241 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840