Protein Alignment CG4053 and ELANE

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001963.1
• Gene: ELANE / 1991
• HGNCID: 3309
• Length: 267
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 72/263 - (27%)
• Similarity: 123/263 - (46%)
• Gaps: 39/263 - (14%)

  Fly     4 RLSLIWL------LLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICS 62
            ||:.::|      ||||.:             .|.:.||||:.|.....|:.||:| :...|.|.
Human     6 RLACLFLACVLPALLLGGT-------------ALASEIVGGRRARPHAWPFMVSLQ-LRGGHFCG 56

  Fly    63 GVILNEQWILTAGHCALDFSIEDLRIIVGTND--RLEPGQTLFPDEALVHCLYDIPYVYNNDIAL 125
            ..::...::::|.||..:.::..:|:::|.::  |.||.:.:|..:.:....|| |....|||.:
Human    57 ATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYD-PVNLLNDIVI 120

  Fly   126 IHVNESIIFNDRTQIVELSREQPPAGSTV--TLTGWGAPESSYPTVQYLQTLNLTIIAHEECRER 188
            :.:|.|...|...|:.:|..:....|:.|  ...|||....:......||.||:|::. ..||.
Human   121 LQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR- 183

  Fly   189 WDFHDGIDIGHICTFTREGE-GACSGDSGGPLMWEGKLVGLVNWGR-ACGVGM-PDMYANTVYYQ 250
                     .::||..|..: |.|.||||.||:..|.:.|:.::.| .|..|: ||.:|....:.
Human   184 ---------SNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFV 239

  Fly   251 DWI 253
            :||
Human   240 NWI 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	64/226 (28%)
ELANE	NP_001963.1	Tryp_SPc	30..245	CDD:238113	64/226 (28%)