Protein Alignment CG4053 and CFD

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 67/231 - (29%)
• Similarity: 108/231 - (46%)
• Gaps: 18/231 - (7%)

  Fly    34 RIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTAGHCALDFSIEDLRIIVGTNDRLEP 98
            ||:||:|||....||..|:| :...|:|.||::.|||:|:|.||..|.:...:::::|.:...:|
Human    32 RILGGREAEAHARPYMASVQ-LNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQP 95

  Fly    99 GQTLFPDEALVHCLYDIPY------VYNNDIALIHVNESIIFNDRTQIV---ELSREQPPAGSTV 154
            .    |.:.|...|..:|:      ..::|:.|:.::|........:.:   .:.|:..| |:..
Human    96 E----PSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAP-GTLC 155

  Fly   155 TLTGWGAPESSYPTVQYLQTLNLTIIAHEECRERWDFHDGIDIGHICTFTREGEGACSGDSGGPL 219
            .:.|||....:......||.:.|.::....|..| ..|||.....:.........:|.|||||||
Human   156 DVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRR-THHDGAITERLMCAESNRRDSCKGDSGGPL 219

  Fly   220 MWEGKLVGLVNWG-RACG-VGMPDMYANTVYYQDWI 253
            :..|.|.|:|..| |.|| ...|.:|.....|..||
Human   220 VCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	66/230 (29%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	66/230 (29%)