Protein Alignment CG4053 and CTRL

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001898.1
• Gene: CTRL / 1506
• HGNCID: 2524
• Length: 264
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 86/275 - (31%)
• Similarity: 127/275 - (46%)
• Gaps: 39/275 - (14%)

  Fly     1 MAVRLSLIWLLLLGTSIDVTRGKRLDNRK---LLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICS 62
            :::.|||:   |||:|    .|..:...|   ....|||.|:.|..|..|:|||:|.....|.|.
Human     4 LSLTLSLV---LLGSS----WGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCG 61

  Fly    63 GVILNEQWILTAGHCALDFSIEDLR--IIVGTNDR---LEPGQTLFPDEALVHCLYDIPYVYNND 122
            |.::::.|::||.||    ::...|  :::|..||   .||.|.|....|:.|..:: ....|||
Human    62 GSLISQSWVVTAAHC----NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWN-STTMNND 121

  Fly   123 IALIHVNESIIFNDRTQIVEL--SREQPPAGSTVTLTGWGAPES-SYPTVQYLQTLNLTIIAHEE 184
            :.|:.:.....:..|...|.|  |.|....|.|...||||.... ...|..:||.:.|.::...:
Human   122 VTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQ 186

  Fly   185 CRERWDFHDGIDIGHICTFTREGEGA--CSGDSGGPLM------WEGKLVGLVNWG-RACGVGMP 240
            ||:.|.  ..|....||.   .|.||  |.|||||||:      |  .|:|:|:|| :.|.|..|
Human   187 CRQYWG--SSITDSMICA---GGAGASSCQGDSGGPLVCQKGNTW--VLIGIVSWGTKNCNVRAP 244

  Fly   241 DMYANTVYYQDWIRR 255
            .:|.....:..||.:
Human   245 AVYTRVSKFSTWINQ 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	76/238 (32%)
CTRL	NP_001898.1	Tryp_SPc	34..260	CDD:238113	76/238 (32%)