Protein Alignment CG4053 and Cfd

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 259
• Identity: 72/259 - (27%)
• Similarity: 125/259 - (48%)
• Gaps: 22/259 - (8%)

  Fly    10 LLLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTA 74
            |::||.::...:.:         .||:|||||.....||..|:| :..||:|.|.:|:|||:|:|
Mouse    10 LVILGAAVCAAQPR---------GRILGGQEAAAHARPYMASVQ-VNGTHVCGGTLLDEQWVLSA 64

  Fly    75 GHCALDFSIED--LRIIVGTN--DRLEPGQTLFPDEALVHCLYDIPYVYNNDIALIHVNESIIFN 135
            .|| :|...:|  :::::|.:  ...||.:..:..:::|......|....:|:.|..::::....
Mouse    65 AHC-MDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLG 128

  Fly   136 DRTQIVELSRE--QPPAGSTVTLTGWGAPESSYPTVQYLQTLNLTIIAHEECRERWDFHDG-IDI 197
            ...:.:.|..|  :...|:...:.|||....:......|..|.::|:....|..| .:||| :.|
Mouse   129 PHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLR-TYHDGVVTI 192

  Fly   198 GHICTFTREGEGACSGDSGGPLMWEGKLVGLVNWG-RACGVG-MPDMYANTVYYQDWIRRTHSG 259
            ..:|..:...: .|.||||.||:....:.|:|.|| |.||.| .|.:|.....|:.||....:|
Mouse   193 NMMCAESNRRD-TCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNG 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	67/229 (29%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	67/229 (29%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)