Protein Alignment CG4053 and KLK8

DIOPT Version :9

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 66/246 - (26%)
• Similarity: 118/246 - (47%)
• Gaps: 43/246 - (17%)

  Fly    32 DNRIVGGQEAEDGVAPYQVSI---QTIWKTHICSGVILNEQWILTAGHCAL--------DFSIED 85
            :::::||.|.:....|:|.::   |.:    :|.||::...|:|||.||..        |.|::
Human    75 EDKVLGGHECQPHSQPWQAALFQGQQL----LCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ- 134

  Fly    86 LRIIVGTNDRLEPGQTLFPDEALVHCLYDIPYV--YNNDIALIHVNESIIFNDRTQIVELSREQP 148
                    ::..|.|.:...:::.|..|:...|  :|:|:.|:.:.:......:.:.:.|:....
Human   135 --------NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCT 191

  Fly   149 PAGSTVTLTGWG---APESSYPTVQYLQTLN---LTIIAHEECRERWDFHDG-IDIGHICTFTRE 206
            ..|...|::|||   :|..::|     .|||   :.|...::|.   |.:.| |..|.:|..:.:
Human   192 QPGQKCTVSGWGTVTSPRENFP-----DTLNCAEVKIFPQKKCE---DAYPGQITDGMVCAGSSK 248

  Fly   207 GEGACSGDSGGPLMWEGKLVGLVNWGR-ACG-VGMPDMYANTVYYQDWIRR 255
            |...|.|||||||:.:|.|.|:.:||. .|| ...|.:|.|...|.|||::
Human   249 GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	64/240 (27%)
		Tryp_SPc	35..256	CDD:238113	66/243 (27%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	64/240 (27%)
		Tryp_SPc	78..300	CDD:238113	66/243 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147493
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840