Protein Alignment CG4053 and KLK11

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 76/286 - (26%)
• Similarity: 132/286 - (46%)
• Gaps: 49/286 - (17%)

  Fly     5 LSLIWLLLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTH-ICSGVILNE 68
            :.::.|:||..:..:..|         :.||:.|.|.:....|:|.::  ..||. :|...::..
Human    33 MRILQLILLALATGLVGG---------ETRIIKGFECKPHSQPWQAAL--FEKTRLLCGATLIAP 86

  Fly    69 QWILTAGHC------------------ALDFSIEDL-RIIVGT---NDRLEPG--QTLFPDEALV 109
            :|:|||.||                  :.::.:..| |.||..   |.:.|.|  ||....|:..
Human    87 RWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFP 151

  Fly   110 HCLYD--IPYV-YNNDIALIHVNESIIFNDRTQIVELSREQPPAGSTVTLTGWGAPESSYPTVQY 171
            |..::  :|.. :.|||.|:.:...:......:.:.||.....||::..::|||:  :|.|.::.
Human   152 HPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGS--TSSPQLRL 214

  Fly   172 LQTL---NLTIIAHEECRERWDFHDGIDIGHICTFTRE-GEGACSGDSGGPLMWEGKLVGLVNWG 232
            ..||   |:|||.|::|...  :...|....:|...:| |:.:|.|||||||:....|.|:::||
Human   215 PHTLRCANITIIEHQKCENA--YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWG 277

  Fly   233 R-ACGV-GMPDMYANTVYYQDWIRRT 256
            : .|.: ..|.:|.....|.|||:.|
Human   278 QDPCAITRKPGVYTKVCKYVDWIQET 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	70/254 (28%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	69/252 (27%)