Protein Alignment CG4053 and PRSS21

DIOPT Version :10

• Sequence 1: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 83/308 - (26%)
• Similarity: 133/308 - (43%)
• Gaps: 78/308 - (25%)

  Fly     1 MAVRLSLIWLLLLGTSIDVTRGKRLD------------NRKLLDNRIVGGQEAEDGVAPYQVSIQ 53
            |..|.:|:..|||..:     |.|..            .|:::.:|||||::||.|..|:|.|::
Human     1 MGARGALLLALLLARA-----GLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR 60

  Fly    54 TIWKTHICSGVILNEQWILTAGHCALDFSIEDLRIIVGTNDRLEP-------GQ-TLFPDEALVH 110
             :|.:|:|...:|:.:|.|||.||...:|           |..:|       || |..|....:.
Human    61 -LWDSHVCGVSLLSHRWALTAAHCFETYS-----------DLSDPSGWMVQFGQLTSMPSFWSLQ 113

  Fly   111 CLYDIPYVYN------------NDIALIHVNESIIFNDRTQIVELSREQPPAGSTVT-------- 155
            ..|...:|.|            .||||:.::..:.:....|.:.|.      .||..
Human   114 AYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQ------ASTFEFENRTDCW 172

  Fly   156 LTGWG--APESSYPTVQYLQTLNLTIIAHEECRE---RWDFHDGIDIGHICTFTRE-GEGACSGD 214
            :||||  ..:.:.|:...||.:.:.||.:..|..   ::.|...|....:|....: |:.||.||
Human   173 VTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGD 237

  Fly   215 SGGPL------MWEGKLVGLVNWGRACG-VGMPDMYANTVYYQDWIRR 255
            |||||      :|  ..:|:|:||..|| ...|.:|.|..::.:||::
Human   238 SGGPLACNKNGLW--YQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQK 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	73/262 (28%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	73/260 (28%)