Protein Alignment CG17475 and KLK7

DIOPT Version :10

• Sequence 1: NP_650600.2
• Gene: CG17475 / 42069
• FlyBaseID: FBgn0038481
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 76/282 - (26%)
• Similarity: 126/282 - (44%)
• Gaps: 66/282 - (23%)

  Fly     7 VQILVILLACTCYKPISAVRLAQLSEDQLEWISKAEGVNFQNRVINGEDVQLGEAKYQISLQGMY 71
            :|||::.||           |....|:       |:|    :::|:|.....|...:|::|  :.
Human     9 LQILLLSLA-----------LETAGEE-------AQG----DKIIDGAPCARGSHPWQVAL--LS 49

  Fly    72 GGHI-CGGCIIDERHVLTAAHCVYGYNPTYLRVIT-GTVEYEKPDAVYFVEEHWIHCNYNSPDYH 134
            |..: |||.:::||.|||||||.......:|...| |....::..|    .:.:.|..|::..:.
Human    50 GNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKA----SKSFRHPGYSTQTHV 110

  Fly   135 NDIALIRLNDTIKFNEYTQPAELPTAPVANGTQLLLTGWGSTELWGDTPDILQKAYLTHVVYSTC 199
            ||:.|::||...:.:...:...||:.....||...::|||:|    .:||:...:.|      .|
Human   111 NDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTT----TSPDVTFPSDL------MC 165

  Fly   200 QEIMNNDPSNGPCHICT---------------LTTGGQGACHGDSGGPLTHNGVLYGLVNWG-YP 248
            .::....|.:     ||               :....:.||:|||||||...|.|.|||:|| :|
Human   166 VDVKLISPQD-----CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFP 225

  Fly   249 CALGVPDS---HANVYYYLEWI 267
            |  |.|:.   :..|..:.:||
Human   226 C--GQPNDPGVYTQVCKFTKWI 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17475	NP_650600.2	Tryp_SPc	50..269	CDD:238113	67/239 (28%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	65/238 (27%)