DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17475 and PRSS3

DIOPT Version :9

Sequence 1:NP_001287372.1 Gene:CG17475 / 42069 FlyBaseID:FBgn0038481 Length:288 Species:Drosophila melanogaster
Sequence 2:XP_011516267.1 Gene:PRSS3 / 5646 HGNCID:9486 Length:333 Species:Homo sapiens


Alignment Length:235 Identity:78/235 - (33%)
Similarity:114/235 - (48%) Gaps:22/235 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 NRVINGEDVQLGEAKYQISLQGMYGGHICGGCIIDERHVLTAAHCVYGYNPTYLRVITGTVEYEK 112
            ::::.|...:.....||:||..  |.|.|||.:|.|:.|::||||.    .|.::|..|    |.
Human   108 DKIVGGYTCEENSLPYQVSLNS--GSHFCGGSLISEQWVVSAAHCY----KTRIQVRLG----EH 162

  Fly   113 PDAVYFVEEHWI-------HCNYNSPDYHNDIALIRLNDTIKFNEYTQPAELPTAPVANGTQLLL 170
            ...|....|.:|       |..||.....|||.||:|:.....|.......|||.|.|.||:.|:
Human   163 NIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTTPPAAGTECLI 227

  Fly   171 TGWGSTELWG-DTPDILQKAYLTHVVYSTCQEIMNNDPSNGPCHICT-LTTGGQGACHGDSGGPL 233
            :|||:|..:| |.||.|:......:..:.|:.......:|.  ..|. ...||:.:|..|||||:
Human   228 SGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNS--MFCVGFLEGGKDSCQRDSGGPV 290

  Fly   234 THNGVLYGLVNWGYPCA-LGVPDSHANVYYYLEWIRSMIS 272
            ..||.|.|:|:||:.|| ...|..:..||.|::||:..|:
Human   291 VCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIA 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17475NP_001287372.1 Tryp_SPc 49..267 CDD:214473 75/227 (33%)
Tryp_SPc 50..269 CDD:238113 77/228 (34%)
PRSS3XP_011516267.1 Tryp_SPc 109..325 CDD:214473 75/227 (33%)
Tryp_SPc 110..328 CDD:238113 77/229 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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