DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17475 and KLK12

DIOPT Version :9

Sequence 1:NP_001287372.1 Gene:CG17475 / 42069 FlyBaseID:FBgn0038481 Length:288 Species:Drosophila melanogaster
Sequence 2:NP_062544.1 Gene:KLK12 / 43849 HGNCID:6360 Length:254 Species:Homo sapiens


Alignment Length:244 Identity:76/244 - (31%)
Similarity:106/244 - (43%) Gaps:58/244 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 RVINGEDVQLGEAKYQISLQGMYGGHI--CGGCIIDERHVLTAAHCVYGYNPTYLRVITGTVEYE 111
            ::.||.:.......:|:   |::.|..  |||.:||.|.|||||||                   
Human    21 KIFNGTECGRNSQPWQV---GLFEGTSLRCGGVLIDHRWVLTAAHC------------------- 63

  Fly   112 KPDAVYFVE--EH------WI----HCNYN---------SPDYHNDIALIRLNDTIKFNEYTQPA 155
             ..:.|:|.  ||      |.    |..::         |..:.:|:.|:||...::.....||.
Human    64 -SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPL 127

  Fly   156 ELPTAPVANGTQLLLTGWGST-ELWGDTPDILQKAYLTHVVYSTCQEIM-NNDPSNGPCHICTLT 218
            .||......||:..::|||.| ......||:||...|:.|.::||..:. ....||   .:|...
Human   128 PLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSN---MVCAGG 189

  Fly   219 TGGQGACHGDSGGPLTHNGVLYGLVNWGY--PCAL-GVPDSHANVYYYL 264
            ..||.||.|||||||...|||.|||:||.  ||.. |:|    .||.|:
Human   190 VPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIP----GVYTYI 234

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17475NP_001287372.1 Tryp_SPc 49..267 CDD:214473 76/244 (31%)
Tryp_SPc 50..269 CDD:238113 76/243 (31%)
KLK12NP_062544.1 Tryp_SPc 21..236 CDD:214473 76/244 (31%)
Tryp_SPc 22..236 CDD:238113 76/243 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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