Protein Alignment CG17475 and KLK2

DIOPT Version :10

• Sequence 1: NP_650600.2
• Gene: CG17475 / 42069
• FlyBaseID: FBgn0038481
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 76/257 - (29%)
• Similarity: 115/257 - (44%)
• Gaps: 51/257 - (19%)

  Fly    47 QNRVINGEDVQLGEAKYQISLQGMYGGHICGGCIIDERHVLTAAHCVYGYNPTYLRVITGTVEYE 111
            |:|::.|.:.:.....:|:::.. :|...|||.::..:.|||||||:...:..:|    |.....
Human    22 QSRIVGGWECEKHSQPWQVAVYS-HGWAHCGGVLVHPQWVLTAAHCLKKNSQVWL----GRHNLF 81

  Fly   112 KPDAV---YFVEEHWIHCNYN-----------SPDYHNDIALIRLNDTIKFNEYTQPAELPTAPV 162
            :|:..   ..|...:.|..||           ..|..:|:.|:||::..|..:..:...|||...
Human    82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEP 146

  Fly   163 ANGTQLLLTGWGSTE--------------LWGDTPDILQKAYLTHVVYSTCQEIMNNDPSNGPCH 213
            |.||....:||||.|              |...:.|:..:||...|.     |.|
Human   147 ALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT-----EFM---------- 196

  Fly   214 ICT-LTTGGQGACHGDSGGPLTHNGVLYGLVNWG-YPCAL-GVPDSHANVYYYLEWIRSMIS 272
            :|. |.|||:..|.|||||||..||||.|:.:|| .|||| ..|..:..|.:|.:||:..|:
Human   197 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17475	NP_650600.2	Tryp_SPc	50..269	CDD:238113	73/249 (29%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	73/250 (29%)