Protein Alignment CG17475 and KLK1

DIOPT Version :10

• Sequence 1: NP_650600.2
• Gene: CG17475 / 42069
• FlyBaseID: FBgn0038481
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 77/256 - (30%)
• Similarity: 116/256 - (45%)
• Gaps: 48/256 - (18%)

  Fly    47 QNRVINGEDVQLGEAKYQISLQGMYGGHICGGCIIDERHVLTAAHCVYGYNPTYLRVITGTVEYE 111
            |:|::.|.:.:.....:|.:|. .:....|||.::..:.|||||||:   :..|...:.....::
Human    22 QSRIVGGWECEQHSQPWQAALY-HFSTFQCGGILVHRQWVLTAAHCI---SDNYQLWLGRHNLFD 82

  Fly   112 KPDAVYF--VEEHWIHCNYN-----------SPDYHNDIALIRLN---DTIKFNEYTQPAELPTA 160
            ..:...|  |.|.:.|..:|           ..||.:|:.|:||.   |||  .:..:..||||.
Human    83 DENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTI--TDAVKVVELPTE 145

  Fly   161 PVANGTQLLLTGWGSTELWG-DTPDILQKAYLTHVVYSTCQEIMNNDPSNGPCHICTLT------ 218
            ....|:..|.:||||.|... ..||.||...|         :|:.||... ..|:..:|
Human   146 EPEVGSTCLASGWGSIEPENFSFPDDLQCVDL---------KILPNDECK-KAHVQKVTDFMLCV 200

  Fly   219 ---TGGQGACHGDSGGPLTHNGVLYGLVNWGY-PCALGVPDSHA---NVYYYLEWIRSMIS 272
               .||:..|.|||||||..:|||.|:.:||| ||  |.|:..:   .|..|::||...|:
Human   201 GHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPC--GTPNKPSVAVRVLSYVKWIEDTIA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17475	NP_650600.2	Tryp_SPc	50..269	CDD:238113	74/248 (30%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	74/249 (30%)