Protein Alignment CG17475 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_650600.2
• Gene: CG17475 / 42069
• FlyBaseID: FBgn0038481
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 91/317 - (28%)
• Similarity: 142/317 - (44%)
• Gaps: 55/317 - (17%)

  Fly     2 VRLGVVQILVILLACT-----CYKPISAVRLA-----QLSEDQLEWISK-----AEG-------- 43
            :|||::.:.::.:..:     .|.|....||.     ..|..|.|.:.|     .||
Human     1 MRLGLLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAHAEDCG 65

  Fly    44 ------VNFQNRVINGEDVQLGEAKYQISLQGMYGG---HICGGCIIDERHVLTAAHCVY-GYNP 98
                  |...:|:|.|.:.|.|...:.:|||..||.   |:|||.::.||.|||||||.. ..:|
Human    66 TAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDP 130

  Fly    99 TYLRVITGT--VEYEKPDAVYF-VEEHWIHCNYNSPDYHNDIALIRLNDTIKFNEYTQPAELP-- 158
            .....:.||  :....|..... ::...||.|:....|.|||||..|...:::|:|.||..||
Human   131 LMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFD 195

  Fly   159 TAPVANG-TQLLLTGWGSTELWGDTPDILQKAYLTHVVYSTCQEIMNNDPSNGPCHICTLTTGG- 221
            ...:.:| |:..::|||.|:..|:..:|||.|.:.::    .:|:.|::.|.|.....|....|
Human   196 VFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYI----SREMCNSERSYGGIIPNTSFCAGD 256

  Fly   222 -QGA---CHGDSGGPLT------HNGVLYGLVNWGYPCA-LGVPDSHANVYYYLEWI 267
             .||   |.|||||||.      ....:.|:.::|:.|. .|.|..:....:|.:|:
Human   257 EDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17475	NP_650600.2	Tryp_SPc	50..269	CDD:238113	76/240 (32%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		5/21 (24%)
		Tryp_SPc	78..316	CDD:238113	76/240 (32%)