Protein Alignment CG17475 and KLK8

DIOPT Version :10

• Sequence 1: NP_650600.2
• Gene: CG17475 / 42069
• FlyBaseID: FBgn0038481
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 70/242 - (28%)
• Similarity: 118/242 - (48%)
• Gaps: 20/242 - (8%)

  Fly    39 SKAEGVNFQNRVINGEDVQLGEAKYQISL-QGMYGGHICGGCIIDERHVLTAAHCVYGYNPTY-L 101
            |:|:    :::|:.|.:.|.....:|.:| ||..  .:|||.::....|||||||   ..|.| :
Human    71 SRAQ----EDKVLGGHECQPHSQPWQAALFQGQQ--LLCGGVLVGGNWVLTAAHC---KKPKYTV 126

  Fly   102 RVITGTVE-YEKPDAVYFVEEHWIHCNYNS---PDYHNDIALIRLNDTIKFNEYTQPAELPTAPV 162
            |:...::: .:.|:....|.:...|..|||   .|:::|:.|::|.|........:|..|.....
Human   127 RLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCT 191

  Fly   163 ANGTQLLLTGWGS-TELWGDTPDILQKAYLTHVVYSTCQEIMNNDPSNGPCHICTLTTGGQGACH 226
            ..|.:..::|||: |....:.||.|..|.:.......|::......::|  .:|..::.|...|.
Human   192 QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG--MVCAGSSKGADTCQ 254

  Fly   227 GDSGGPLTHNGVLYGLVNWGY-PCALG-VPDSHANVYYYLEWIRSMI 271
            |||||||..:|.|.|:.:||. ||... .|..:.|:..||:||:.:|
Human   255 GDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17475	NP_650600.2	Tryp_SPc	50..269	CDD:238113	67/227 (30%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	65/226 (29%)