Protein Alignment CG31265 and PRSS1

DIOPT Version :10

• Sequence 1: NP_650599.1
• Gene: CG31265 / 42068
• FlyBaseID: FBgn0051265
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 90/265 - (33%)
• Similarity: 136/265 - (51%)
• Gaps: 31/265 - (11%)

  Fly     8 LLILLAVKPPNPCESKRIVGPFPAGQSGRIKGGEEAEIGFAPYQVSLQPIVGSHNCGGAILNENW 72
            ||||..|       :..:..||  ....:|.||...|....||||||..  |.|.|||:::||.|
Human     4 LLILTFV-------AAALAAPF--DDDDKIVGGYNCEENSVPYQVSLNS--GYHFCGGSLINEQW 57

  Fly    73 IITAGHCVENFIPAL-----VNVITGTNKWAEPGAIYYTAEIHKHCMYDQPYMHNDIALVKLTEN 132
            :::||||.::.|...     :.|:.|..::..      .|:|.:|..||:..::|||.|:||:..
Human    58 VVSAGHCYKSRIQVRLGEHNIEVLEGNEQFIN------AAKIIRHPQYDRKTLNNDIMLIKLSSR 116

  Fly   133 ITFNELTQPIALPTRPVQLGEEIVLTGWGSDVAYGSSMED-LHKLTVGLVPLDECYETF--NRTS 194
            ...|.....|:|||.|...|.:.:::|||:..:.|:...| |..|...::...:|..::  ..||
Human   117 AVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITS 181

  Fly   195 SMGVGHICT-FSREGEGACHGDSGGPLVSNGQLVGVVNWGRPCG-VGLPDVQANVYYYLDWIRSK 257
            :|    .|. |...|:.:|.||||||:|.||||.|||:||..|. ...|.|...||.|:.||::.
Human   182 NM----FCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNT 242

  Fly   258 LSGNN 262
            ::.|:
Human   243 IAANS 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31265	NP_650599.1	Tryp_SPc	39..257	CDD:238113	81/227 (36%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	80/227 (35%)