Protein Alignment CG17477 and PRSS22

DIOPT Version :10

• Sequence 1: NP_650598.1
• Gene: CG17477 / 42067
• FlyBaseID: FBgn0038479
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 72/263 - (27%)
• Similarity: 119/263 - (45%)
• Gaps: 57/263 - (21%)

  Fly    27 IVGGQNAAEGDAPYQVSLQTLLGSHLCGGAIISDRWIITAGHCVK------------------GY 73
            :|||:::.:.:.|:.||:|. .|:|.|.|::::.||:|||.||.|                  |.
Human   158 VVGGEDSTDSEWPWIVSIQK-NGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGN 221

  Fly    74 PTSRLQVATGTIRYAEPGAVYYPDAIYLHCNYDSPKYQN----DIGLLHLNESITFNALTQAVEL 134
            |.||.|..  .:.:.||..||              .::.    ||.|:.|..||.|:.....:.|
Human   222 PGSRSQKV--GVAWVEPHPVY--------------SWKEGACADIALVRLERSIQFSERVLPICL 270

  Fly   135 PTSPF---PRGASELVFTGWGSQSAAGSL--PSQLQRVQQQHLNSPACESMMSAYEDLELGPC-- 192
            |.:..   |.  :....:||||......|  |..||:::...::|..|..:.  :.....||.
Human   271 PDASIHLPPN--THCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLY--WRGAGQGPITE 331

  Fly   193 -HICA-YRQANIGACHGDSGGPLVHQ----GTLVGILNFFVPCAQ-GVPDIFMNIMYYRDWMRQT 250
             .:|| |.:....||.|||||||:.|    ..|.||:::...||: ..|.:::::..:|.|:.:.
Human   332 DMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKI 396

  Fly   251 MSG 253
            :.|
Human   397 VQG 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17477	NP_650598.1	Tryp_SPc	27..250	CDD:238113	71/258 (28%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	71/258 (28%)