DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17477 and PRSS1

DIOPT Version :9

Sequence 1:	NP_650598.1	Gene:	CG17477 / 42067	FlyBaseID:	FBgn0038479	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	233	Identity:	78/233 - (33%)
Similarity:	122/233 - (52%)	Gaps:	15/233 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 IVGGQNAAEGDAPYQVSLQTLLGSHLCGGAIISDRWIITAGHCVKGYPTSRLQVATG--TIRYAE 89
            ||||.|..|...||||||.:  |.|.|||::|:::|:::||||.|    ||:||..|  .|...|
Human   249 IVGGYNCEENSVPYQVSLNS--GYHFCGGSLINEQWVVSAGHCYK----SRIQVRLGEHNIEVLE 307

  Fly    90 PGAVYYPDA-IYLHCNYDSPKYQNDIGLLHLNESITFNALTQAVELPTSPFPRGASELVFTGWGS 153
            ....:...| |..|..||.....|||.|:.|:.....||....:.|||:| |...::.:.:|||:
Human   308 GNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAP-PATGTKCLISGWGN 371

  Fly   154 QSAAGS-LPSQLQRVQQQHLNSPACESMMSAYEDLELGPCHICAYRQANIGACHGDSGGPLVHQG 217
            .:::|: .|.:||.:....|:...||   ::|............:.:....:|.||||||:|..|
Human   372 TASSGADYPDELQCLDAPVLSQAKCE---ASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNG 433

  Fly   218 TLVGILNFFVPCAQ-GVPDIFMNIMYYRDWMRQTMSGN 254
            .|.|::::...||| ..|.::..:..|..|::.|::.|
Human   434 QLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17477	NP_650598.1	Tryp_SPc	27..250	CDD:238113	76/227 (33%)
CG17477	NP_650598.1	Tryp_SPc	27..246	CDD:214473	75/223 (34%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	75/224 (33%)
		Tryp_SPc	249..467	CDD:238113	76/227 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920