Protein Alignment CG17477 and HPN

DIOPT Version :10

• Sequence 1: NP_650598.1
• Gene: CG17477 / 42067
• FlyBaseID: FBgn0038479
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 77/260 - (29%)
• Similarity: 123/260 - (47%)
• Gaps: 39/260 - (15%)

  Fly    27 IVGGQNAAEGDAPYQVSLQTLLGSHLCGGAIISDRWIITAGHCVKGYP-----TSRLQVATGTIR 86
            ||||::.:.|..|:||||: ..|:|||||:::|..|::||.||   :|     .||.:|..|.:.
Human   163 IVGGRDTSLGRWPWQVSLR-YDGAHLCGGSLLSGDWVLTAAHC---FPERNRVLSRWRVFAGAVA 223

  Fly    87 YAEP-GAVYYPDAIYLHCNY------DSPKYQNDIGLLHLNESITFNALTQAVELPTSPFPRGAS 144
            .|.| |......|:..|..|      :|.:..|||.|:||:..:......|.|.||.:     ..
Human   224 QASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAA-----GQ 283

  Fly   145 ELV------FTGWGSQSAAGSLPSQLQRVQQQHLNSPACESMMSAYEDLELGPCHICA-YRQANI 202
            .||      .||||:....|.....||..:...:::..|..  :.:...::.|...|| |.:..|
Human   284 ALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNG--ADFYGNQIKPKMFCAGYPEGGI 346

  Fly   203 GACHGDSGGPLVHQGT--------LVGILNFFVPCAQG-VPDIFMNIMYYRDWMRQTMSGNGKCA 258
            .||.||||||.|.:.:        |.||:::...||.. .|.::..:..:|:|:.|.:..:.:.:
Human   347 DACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEAS 411

  Fly   259  258
            Human   412  411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17477	NP_650598.1	Tryp_SPc	27..250	CDD:238113	76/250 (30%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736
		Tryp_SPc	163..400	CDD:238113	75/247 (30%)