Protein Alignment GckIII and Stk25

DIOPT Version :9

• Sequence 1: NP_650596.1
• Gene: GckIII / 42064
• FlyBaseID: FBgn0266465
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_067512.3
• Gene: Stk25 / 59041
• MGIID: 1891699
• Length: 426
• Species: Mus musculus
• Alignment Length: 626
• Identity: 277/626 - (44%)
• Similarity: 327/626 - (52%)
• Gaps: 221/626 - (35%)

  Fly     6 KVDPELIFTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCDSPY 70
            :||||.:|||.:||||||||||:|||||.|::||||||||||||||||:||||||.|||||||||
Mouse    13 RVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 77

  Fly    71 VTKYYGSFLKGTKLWIIMEYLGGGSALDLMKAGSFEEMHIGIILREVLKGLDYLHSERKLHRDIK 135
            :|:|:||:||.||||||||||||||||||:|.|..||.:|..||||:||||||||||||:|||||
Mouse    78 ITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIK 142

  Fly   136 AANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIE 200
            ||||||||||||||||||||||||:|..||||||||||||||||||||.||.|||||||||||||
Mouse   143 AANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIE 207

  Fly   201 LAKGEPPNSELHPMRVLFLIPKNNPPQLTGSYTKSFKDFVEACLNKDPENRPTAKELLKYPFIKK 265
            |||||||||:||||||||||||||||.|.|.::|.||:||||||||||..|||||||||:.||.:
Mouse   208 LAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITR 272

  Fly   266 -AKKNAYLIDLIDRFKKWKVSKGDESETESENSDSDSDAKQGGSSQDEPWIMTVKGLHINSAPRA 329
             .||.::|.:||||:|:|| |:|...|:.||:||.|.:|:.|  .|...|
Mouse   273 YTKKTSFLTELIDRYKRWK-SEGHGEESSSEDSDIDGEAEDG--EQGPIW--------------- 319

  Fly   330 GVNSFQLQEHELTMQKLMQTTHSPAGGGGVQASPAANALSSSVSAVAASASSVSVITANEGVSSA 394
                                                                             
Mouse   320 ----------------------------------------------------------------- 319

  Fly   395 SALPPQNSHVHNHNHNNINNNNIRNLSNKHATTTMLNAAPPPSSVTSSSSASELQQKRSSSKPEL 459
             ..||                .||               |.|.|.....:|     ..||.||
Mouse   320 -TFPP----------------TIR---------------PSPHSKLHKGTA-----LHSSQKP-- 345

  Fly   460 RQSRSAAPLDQVEDRRASLGLPLQSSVPTPSTAEQQQQRRSSQRESFHANNAALVASCSSSSNNH 524
                 |.|:.:
Mouse   346 -----AEPIKR------------------------------------------------------ 351

  Fly   525 SHEEHVATNHASHVKHSGAGQRLVQTNSACLNNFLFPVLSDIQRKY-SGGGSAGSGGSGGRNIGV 588
                                    |..|.||:..:.||..:::.|: ..|||.|:
Mouse   352 ------------------------QPRSQCLSTLVRPVFGELKEKHKQSGGSVGA---------- 382

  Fly   589 GSDIGDLKSVFELAERSSPGVSDLFMKELIHMLVPGYSETR 629
               :.:|::.|.|||.|.||:||..|..|:.. |..:|.:|
Mouse   383 ---LEELENAFSLAEESCPGISDKLMVHLVER-VQRFSHSR 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GckIII	NP_650596.1	STKc_MST3_like	12..283	CDD:270786	219/271 (81%)
		S_TKc	13..263	CDD:214567	209/249 (84%)
Stk25	NP_067512.3	STKc_STK25	15..291	CDD:270810	222/275 (81%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..354		28/267 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833225
Domainoid	1	1.000	440	1.000	Domainoid score	I549
eggNOG	1	0.900	-	-		E1_KOG0201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	518	1.000	Inparanoid score	I1268
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000324
OrthoInspector	1	1.000	-	-		otm43118
orthoMCL	1	0.900	-	-		OOG6_100860
Panther	1	1.100	-	-	LDO	PTHR48012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R966
SonicParanoid	1	1.000	-	-		X488
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.780