DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GckIII and stk4

DIOPT Version :9

Sequence 1:	NP_650596.1	Gene:	GckIII / 42064	FlyBaseID:	FBgn0266465	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	NP_989249.1	Gene:	stk4 / 394860	XenbaseID:	XB-GENE-955920	Length:	485	Species:	Xenopus tropicalis

Alignment Length:	301	Identity:	150/301 - (49%)
Similarity:	208/301 - (69%)	Gaps:	12/301 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PELIFTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCDSPYVTK 73
            ||.:|...|::|:||:|.|:|.....|.|:||||.|.:   |.::.:|.:||.::.||||.:|.|
Frog    26 PEEVFDVLEKLGEGSYGSVYKASHKETSQIVAIKQIPV---ESDLQEIIKEIAIMQQCDSLHVVK 87

  Fly    74 YYGSFLKGTKLWIIMEYLGGGSALDL--MKAGSFEEMHIGIILREVLKGLDYLHSERKLHRDIKA 136
            ||||:.|.|.|||:||:.||||..|:  ::..:.:|.....||:..||||:|||..||:||||||
Frog    88 YYGSYFKNTDLWIVMEFCGGGSISDIIRLRKQTLKEDETATILQSTLKGLEYLHFMRKIHRDIKA 152

  Fly   137 ANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIEL 201
            .|:||:.:|..||||||||||||:|.:||||.:|||||||||||::..|:..||||||||||||:
Frog   153 GNILLNSEGTAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEM 217

  Fly   202 AKGEPPNSELHPMRVLFLIPKNNPPQLTGS--YTKSFKDFVEACLNKDPENRPTAKELLKYPFIK 264
            |:|:||.:|:||||.:|:||.|.||.....  ::|.|.||:..||.|:||.|.:|.|||::||||
Frog   218 AEGKPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQHPFIK 282

  Fly   265 KAKKNAYLIDLID-----RFKKWKVSKGDESETESENSDSD 300
            .||..:.|..||:     :.|:.::.:.:....|.||:|.|
Frog   283 TAKGESILRHLINEAQDAKLKRTELKQREVEPEEEENADED 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GckIII	NP_650596.1	STKc_MST3_like	12..283	CDD:270786	143/279 (51%)
GckIII	NP_650596.1	S_TKc	13..263	CDD:214567	134/253 (53%)
stk4	NP_989249.1	STKc_MST1_2	26..281	CDD:132943	136/257 (53%)
stk4	NP_989249.1	Mst1_SARAH	431..478	CDD:314497
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D967913at2759
OrthoFinder	1	1.000	-	-		FOG0000324
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920