DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GckIII and ppk2

DIOPT Version :9

Sequence 1:	NP_650596.1	Gene:	GckIII / 42064	FlyBaseID:	FBgn0266465	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	NP_594646.1	Gene:	ppk2 / 2543100	PomBaseID:	SPAC12B10.14c	Length:	665	Species:	Schizosaccharomyces pombe

Alignment Length:	275	Identity:	61/275 - (22%)
Similarity:	119/275 - (43%)	Gaps:	28/275 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TEKVDPELIFT------KQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDE---IDDIQQE 59
            |:| ||...:|      :|:.:|      .:.......::||.||..|:......   ::::|:
pombe   380 TQK-DPLFFYTDFTKICQQDTVG------TYVARQTLDKEVVVIKRFDISAVTHRRLLLEELQR- 436

  Fly    60 IMVLSQCDSPYVTKYYGSFLKGTKLWIIMEYLGGGSALD-LMKAGSFEEMHIGIILREVLKGLDY 123
               ||......:.:|..||.....:|.:.||....:.|. |:....|.|::|..|..|:..||.:
pombe   437 ---LSGLSHKNLIRYNESFWYLNNIWSVFEYKDPSTKLSALIPKYFFSELNIASICYEISSGLAF 498

  Fly   124 LHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAK 188
            ||:....|.::....:.|::...:|:.::..:.......:.|......|.|:..:..|:.   ..
pombe   499 LHNSGIAHHNLTTECIYLTKSSCLKIGNYAFSSPYIERQTNRGAVSHVPDWLIEKNYKEG---FM 560

  Fly   189 ADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNN--PPQLTGSYTKSFKDFVEACLNKDPENR 251
            .|:.|||:.|:|:.:|: ||.....::.:.|.|..|  ..::.|..::.||:|:...|..:....
pombe   561 KDVKSLGLVALEIFQGQ-PNFFRKSIQSIQLTPNANVLVNRVRGLISQEFKEFLLQTLQAETLQG 624

  Fly   252 PTAKELLK-YPFIKK 265
            |....||: ..|::|
pombe   625 PNINMLLETSSFLEK 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GckIII	NP_650596.1	STKc_MST3_like	12..283	CDD:270786	57/267 (21%)
GckIII	NP_650596.1	S_TKc	13..263	CDD:214567	55/262 (21%)
ppk2	NP_594646.1	DUF863	59..>320	CDD:283539
ppk2	NP_594646.1	PKc_like	387..638	CDD:304357	56/264 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48012
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100