| Sequence 1: | NP_732202.2 | Gene: | Keap1 / 42062 | FlyBaseID: | FBgn0038475 | Length: | 776 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036421.2 | Gene: | KEAP1 / 9817 | HGNCID: | 23177 | Length: | 624 | Species: | Homo sapiens |
| Alignment Length: | 615 | Identity: | 291/615 - (47%) |
|---|---|---|---|
| Similarity: | 394/615 - (64%) | Gaps: | 23/615 - (3%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 19 PNHKGYPCR--------PEEAEMSNTSESCSISCGGRFGSAHSTLDDHDATDDDMTFCMSNYAKE 75
Fly 76 ALKMMYMMRSHGMLTDVVLEVKKE-----LFPAHKVVLSAASPYFKAMFTGGLKESEMSRVQLQG 135
Fly 136 VCPTAMSRILYFMYTGQIRVTEVTVCQLLPAATMFQVPNVIDACCAFLERQLDPTNAIGIAHFAE 200
Fly 201 QHGCVELQKKANVFIERNFTQVCQEEEFLQLSAYQLIALIRRDELNVQEEREVYNAVLKWVKYDE 265
Fly 266 DNRHCKMEHILGAVRCQFLTPNFLKEQMKNCDVLRKVPACREYLAKIFKDLTLHKCPGVKE-RTP 329
Fly 330 NTTRMIFVAGGFFRHSLDILEAYNVDDMTWTTLANLRIPRSGLGAAFLKGKFYAVGGRNNNIGSS 394
Fly 395 YDSDWVDRYSAVTETWRPCAPMSVPRHRVGVAVMDELMYAVGGSAGMEYHNTVEYYDPDLDRWTL 459
Fly 460 VQPMHAKRLGVGVVVVNRLLYAIGGFDGNERLASVECYHPENNEWSFLPPLQTGRSGAGVAAINQ 524
Fly 525 YIYVVGGFDGTRQLATVERYDTENDTWDMVAPIQIARSALSLTPLDEKLYAIGGFDGNNFLSIVE 589
Fly 590 VYDPRTNTWTTGTPLKSGRSGHASAVIYQP 619 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Keap1 | NP_732202.2 | BTB | 80..183 | CDD:279045 | 44/107 (41%) |
| PHA03098 | 92..599 | CDD:222983 | 263/512 (51%) | ||
| BACK | 192..294 | CDD:285009 | 54/101 (53%) | ||
| Kelch | 335..379 | CDD:128874 | 24/43 (56%) | ||
| KELCH repeat | 369..416 | CDD:276965 | 22/46 (48%) | ||
| Kelch | 382..430 | CDD:128874 | 27/47 (57%) | ||
| KELCH repeat | 420..463 | CDD:276965 | 23/42 (55%) | ||
| Kelch | 433..476 | CDD:128874 | 25/42 (60%) | ||
| KELCH repeat | 467..510 | CDD:276965 | 28/42 (67%) | ||
| Kelch | 478..523 | CDD:128874 | 27/44 (61%) | ||
| KELCH repeat | 514..558 | CDD:276965 | 25/43 (58%) | ||
| Kelch_1 | 514..556 | CDD:279660 | 23/41 (56%) | ||
| KELCH repeat | 561..606 | CDD:276965 | 21/44 (48%) | ||
| Kelch | 572..616 | CDD:128874 | 22/43 (51%) | ||
| KEAP1 | NP_036421.2 | BTB_POZ_KLHL19_KEAP1 | 56..180 | CDD:349557 | 49/123 (40%) |
| PHA03098 | 95..596 | CDD:222983 | 259/500 (52%) | ||
| Kelch 1 | 327..372 | 24/44 (55%) | |||
| KELCH repeat | 362..409 | CDD:276965 | 22/46 (48%) | ||
| Kelch 2 | 373..423 | 27/49 (55%) | |||
| KELCH repeat | 413..456 | CDD:276965 | 23/42 (55%) | ||
| Kelch 3 | 424..470 | 25/45 (56%) | |||
| KELCH repeat | 460..503 | CDD:276965 | 28/42 (67%) | ||
| Kelch 4 | 471..517 | 27/45 (60%) | |||
| KELCH repeat | 507..551 | CDD:276965 | 25/43 (58%) | ||
| Kelch 5 | 518..564 | 24/45 (53%) | |||
| KELCH repeat | 554..597 | CDD:276965 | 21/42 (50%) | ||
| Kelch 6 | 565..611 | 23/45 (51%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 108 | 1.000 | Domainoid score | I6494 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG4441 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H8184 | |
| Inparanoid | 1 | 1.050 | 561 | 1.000 | Inparanoid score | I1096 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG46913 | |
| OrthoDB | 1 | 1.010 | - | - | D312716at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0007175 | |
| OrthoInspector | 1 | 1.000 | - | - | oto91208 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_107392 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24412 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5397 |
| SonicParanoid | 1 | 1.000 | - | - | X9 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.870 | |||||