DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Keap1 and AT1G27420

DIOPT Version :9

Sequence 1:	NP_732202.2	Gene:	Keap1 / 42062	FlyBaseID:	FBgn0038475	Length:	776	Species:	Drosophila melanogaster
Sequence 2:	NP_174062.1	Gene:	AT1G27420 / 839632	AraportID:	AT1G27420	Length:	346	Species:	Arabidopsis thaliana

Alignment Length:	277	Identity:	65/277 - (23%)
Similarity:	108/277 - (38%)	Gaps:	74/277 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 RSGLGAAFLK-GKFYAVGGRNNNIGSSYDSDWVDRYSAVTE------TWRPCAPMSVPRHRVGVA 426
            :.|.|.|.|. ||....||.....||..:|..|...:.|.|      :||..|.|::||:....|
plant    99 KRGFGVAVLDGGKIVFFGGYTEVEGSGINSTTVSASADVYEFDPANNSWRKLAGMNIPRYNFAFA 163

  Fly   427 VMDELMYAVGGSAGMEYHNTVEYYDPDLDRWTLVQPMHAKRLGVGVVVVNRLLYAIGGFDGNERL 491
            .::.|:|.:.|      ::|..|                                        .|
plant   164 EVNGLLYVIRG------YSTDTY----------------------------------------SL 182

  Fly   492 ASVECYHPENNEWSFL--PPLQTGRSGAGVAAINQYIYVVGGFDGTRQLATVERYDTENDTWDMV 554
            ::.|.|:|:.|:||.:  |.....|..|  .|.:..:|.||  :|:|   .::.||.:..||:.:
plant   183 SNAEVYNPKTNQWSLMHCPNRPVWRGFA--FAFSSKLYAVG--NGSR---FIDIYDPKTQTWEEL 240

  Fly   555 APIQIARSALSLTPLDEKLYAIGGFDGNNFLSIVEVYDPRTNTWTT-GTPLKSG----RSG--HA 612
            ...| :.|..|.|.:..|:|    |...|....:.|:||..|:|:: ..|.:.|    |.|  :.
plant   241 NSEQ-SVSVYSYTVVRNKVY----FMDRNMPGRLGVFDPEENSWSSVFVPPREGGFWVRLGVWNN 300

  Fly   613 SAVIYQPACSTTFMDYE 629
            ..:::...|....:.|:
plant   301 KVLLFSRVCGHETLMYD 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Keap1	NP_732202.2	BTB	80..183	CDD:279045
		PHA03098	92..599	CDD:222983	58/238 (24%)
		BACK	192..294	CDD:285009
		Kelch	335..379	CDD:128874	4/10 (40%)
		KELCH repeat	369..416	CDD:276965	17/53 (32%)
		Kelch	382..430	CDD:128874	15/53 (28%)
		KELCH repeat	420..463	CDD:276965	7/42 (17%)
		Kelch	433..476	CDD:128874	4/42 (10%)
		KELCH repeat	467..510	CDD:276965	8/44 (18%)
		Kelch	478..523	CDD:128874	11/46 (24%)
		KELCH repeat	514..558	CDD:276965	12/43 (28%)
		Kelch_1	514..556	CDD:279660	12/41 (29%)
		KELCH repeat	561..606	CDD:276965	13/45 (29%)
		Kelch	572..616	CDD:128874	13/50 (26%)
AT1G27420	NP_174062.1	F-box	9..50	CDD:395521
		PHA03098	<81..286	CDD:222983	59/244 (24%)
		KELCH repeat	100..153	CDD:276965	17/52 (33%)
		KELCH repeat	157..202	CDD:276965	14/90 (16%)
		KELCH repeat	205..242	CDD:276965	12/43 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960