DRSC/TRiP Functional Genomics Resources

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Protein Alignment Keap1 and SKIP6

DIOPT Version :9

Sequence 1:NP_732202.2 Gene:Keap1 / 42062 FlyBaseID:FBgn0038475 Length:776 Species:Drosophila melanogaster
Sequence 2:NP_565522.1 Gene:SKIP6 / 816731 AraportID:AT2G21950 Length:372 Species:Arabidopsis thaliana


Alignment Length:220 Identity:60/220 - (27%)
Similarity:89/220 - (40%) Gaps:60/220 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   335 IFVAGGFFR----HSLDILEA-YNVDDMTWTTLANLRIPRSGLGAAFLKGKFYAVGG-------R 387
            |:|.||..|    .|:.:|:. ::    ||..::|:|:.|....|..:.||.|.:||       |
plant   128 IYVIGGSIRDVPSSSVWVLDCRFH----TWRRVSNMRVGREFAAAGVIDGKIYVIGGCVVDNWAR 188

  Fly   388 NNNIGSSYDSDWVDRYSAVTETWRPCAPMSVPRHRVGVAVMDELMYAVGGSAGMEY----HNTVE 448
            :.|        |.:.:...|:||.|.|       ..|:.|.::.|:|.....|..|    .|.| 
plant   189 SIN--------WAEMFDIKTQTWEPVA-------SPGMEVREKWMHASAVMEGKVYAMADRNGV- 237

  Fly   449 YYDPDLDRWTLVQPMHAKRLGVG----VVVVNRLLYA------IGGFDGNER----LASVE---- 495
            .|:|...:|    .|..|||.:|    ..|:..:||.      |.|:|..||    |..||    
plant   238 VYEPKEKKW----EMPEKRLDLGWRGRACVIENILYCYDYLGKIRGYDPKERIWRELKGVESLPK 298

  Fly   496 --CYHPENNEWSFLPPLQTGRSGAG 518
              |.....|....|..|..|::|:|
plant   299 FLCGATMANRGGKLTVLWEGKAGSG 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Keap1NP_732202.2 BTB 80..183 CDD:279045
PHA03098 92..599 CDD:222983 60/220 (27%)
BACK 192..294 CDD:285009
Kelch 335..379 CDD:128874 13/48 (27%)
KELCH repeat 369..416 CDD:276965 15/53 (28%)
Kelch 382..430 CDD:128874 13/54 (24%)
KELCH repeat 420..463 CDD:276965 11/46 (24%)
Kelch 433..476 CDD:128874 14/50 (28%)
KELCH repeat 467..510 CDD:276965 17/62 (27%)
Kelch 478..523 CDD:128874 17/57 (30%)
KELCH repeat 514..558 CDD:276965 2/5 (40%)
Kelch_1 514..556 CDD:279660 2/5 (40%)
KELCH repeat 561..606 CDD:276965
Kelch 572..616 CDD:128874
SKIP6NP_565522.1 F-box 21..64 CDD:279040
Kelch_1 117..160 CDD:279660 10/35 (29%)
KELCH repeat 122..159 CDD:276965 9/34 (26%)
muta_rot_YjhT 153..>352 CDD:274641 52/191 (27%)
KELCH repeat 163..212 CDD:276965 16/63 (25%)
Kelch_1 163..210 CDD:279660 15/61 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 57 1.000 Inparanoid score I2576
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X9
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.960

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