DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment Keap1 and KLHL24

DIOPT Version :10

Sequence 1:	NP_732202.2	Gene:	Keap1 / 42062	FlyBaseID:	FBgn0038475	Length:	776	Species:	Drosophila melanogaster
Sequence 2:	NP_001336342.1	Gene:	KLHL24 / 54800	HGNCID:	25947	Length:	625	Species:	Homo sapiens

Alignment Length:	14	Identity:	5/14 - (35%)
Similarity:	11/14 - (78%)	Gaps:	0/14 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 ASLGLTSNEAVITA 72
            :|:..:|.|:|:|:
Human   262 SSISSSSKESVVTS 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Keap1	NP_732202.2	PHA03098	92..599	CDD:222983
		KELCH repeat	369..416	CDD:276965
		KELCH repeat	420..463	CDD:276965
		KELCH repeat	467..510	CDD:276965
		KELCH repeat	514..558	CDD:276965
		KELCH repeat	561..606	CDD:276965
KLHL24	NP_001336342.1	BTB_POZ_KLHL24_KRIP6	48..168	CDD:349562
		PHA03098	62..591	CDD:222983	5/14 (36%)
		KELCH repeat	354..393	CDD:276965
		KELCH repeat	397..466	CDD:276965
		KELCH repeat	469..514	CDD:276965
		KELCH repeat	517..556	CDD:276965
		KELCH repeat	559..604	CDD:276965
		Kelch	570..616	CDD:128874
Blue background indicates that the domain is not in the aligned region.

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