Protein Alignment Keap1 and C53A5.11

DIOPT Version :10

• Sequence 1: NP_732202.2
• Gene: Keap1 / 42062
• FlyBaseID: FBgn0038475
• Length: 776
• Species: Drosophila melanogaster
• Sequence 2: NP_506607.2
• Gene: C53A5.11 / 183741
• WormBaseID: WBGene00008269
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 395
• Identity: 93/395 - (23%)
• Similarity: 157/395 - (39%)
• Gaps: 58/395 - (14%)

  Fly   224 QEEEFLQLSAYQLIALIRRDELNVQEEREVYNAVLKWVKYD-EDNRHC-KMEHILGAVR--CQFL 284
            |.||.....|.::....|....|:.:..:::..:|.:..|: :||..| .|.|.:.::.  ....
 Worm    27 QSEETQHPKAIEMRNQFRNTTENLIQTLQMFFGILSFELYEGKDNLKCITMIHDITSLMEVADTK 91

  Fly   285 TPNFL-----KEQMKNCD--VLRKVPACREYLAKIFKDLTLHKCPGVKERTPNTTRMIFVAGGFF 342
            ..|::     |||:...|  ||...|..                  |.:|..|:...:|:  |:|
 Worm    92 LKNYINTLNSKEQIFMVDDGVLNMDPIL------------------VADRKQNSREPLFI--GYF 136

  Fly   343 RHSLDILEAYNVDDMTWTTLANLRIPRSGLGAAFLKGKFYAVGGRNN----NIGSSYDSDWVDRY 403
            :          .|.|::..:..|..|:|.........|.:.:||.||    |....:|.:...|.
 Worm   137 K----------PDTMSFMPIGRLPNPKSHYAVVSSSTKVFIIGGMNNGTYLNRVEMFDKEKGIRV 191

  Fly   404 SAVTETWRPCAPMSVPRHRVGVAVMDELMYAVGGSAGMEYHNTVEYYDPDL-DRWTLVQPMHAKR 467
            .        |..:...|.|....:.::.:||||| ....|.::||.||... ..||....::.:|
 Worm   192 E--------CTRLMHGRTRTSACIHEDAIYAVGG-YDATYMSSVEIYDIKTGGDWTTGPSLNNRR 247

  Fly   468 LGVGVVVVNRLLYAIGGFDGNERLASVECYHPENNEWSFLPPLQTGRSGAGVAAINQYIYVVGGF 532
            ....||.....|:.:|||:|.:...::|......:::.....: .||:|.|.......|||.||:
 Worm   248 ADASVVSFYGQLFVLGGFNGKDYEETIEKLSDSKDKFEVCGNM-VGRAGFGACVFRGRIYVAGGW 311

  Fly   533 D-GTRQLATVERYDTENDTWDMVAPIQIARSALSLTPLDEKLYAIGGFDGN-NFLSIVEVYDPRT 595
            : ....|.|.:.||...:||.....:...|....|...:|.:|||.|...: :.:...|.:||:|
 Worm   312 NTPCNTLKTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNEAIYAIRGCSHDWDLIKETERFDPQT 376

  Fly   596 NTWTT 600
            .||.|
 Worm   377 LTWAT 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Keap1	NP_732202.2	PHA03098	92..599	CDD:222983	91/392 (23%)
		KELCH repeat	369..416	CDD:276965	10/50 (20%)
		KELCH repeat	420..463	CDD:276965	14/43 (33%)
		KELCH repeat	467..510	CDD:276965	9/42 (21%)
		KELCH repeat	514..558	CDD:276965	14/44 (32%)
		KELCH repeat	561..606	CDD:276965	14/41 (34%)
C53A5.11	NP_506607.2	NanM	136..360	CDD:442289	60/243 (25%)
		KELCH repeat	153..197	CDD:276965	10/51 (20%)
		KELCH repeat	200..243	CDD:276965	14/43 (33%)
		KELCH repeat	247..290	CDD:276965	9/42 (21%)
		KELCH repeat	293..339	CDD:276965	14/45 (31%)