DRSC/TRiP Functional Genomics Resources

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Protein Alignment Keap1 and LOC108178999

DIOPT Version :9

Sequence 1:NP_732202.2 Gene:Keap1 / 42062 FlyBaseID:FBgn0038475 Length:776 Species:Drosophila melanogaster
Sequence 2:XP_017212974.2 Gene:LOC108178999 / 108178999 -ID:- Length:268 Species:Danio rerio


Alignment Length:252 Identity:92/252 - (36%)
Similarity:135/252 - (53%) Gaps:15/252 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   364 NLRIPRSGLGAAFLKGKFYAVGGRNNNIGSSYDS-------DWVDRYSAVTETWRPCAPMSVPRH 421
            |:...|..:....|..:.|.:||        ||.       :.:|..:.....|...|.|:|.|.
Zfish    14 NIARKRRYVATVALNDRVYVIGG--------YDGRSRLSSVECLDYTADEDGVWYSVATMNVRRG 70

  Fly   422 RVGVAVMDELMYAVGGSAGMEYHNTVEYYDPDLDRWTLVQPMHAKRLGVGVVVVNRLLYAIGGFD 486
            ..|...:.:::|..||..|...|.::|.|||::|:|:::..|...|.|.|:||.:.|:|.:||:|
Zfish    71 LAGATTLGDMIYVAGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGLIYCLGGYD 135

  Fly   487 GNERLASVECYHPENNEWSFLPPLQTGRSGAGVAAINQYIYVVGGFDGTRQLATVERYDTENDTW 551
            |...|.|||.|.|....|:.:.|:...|||||||.:|.:||||||||||..|::||.|:...|.|
Zfish   136 GLNILNSVERYDPHTGHWTSVTPMANKRSGAGVALLNDHIYVVGGFDGTAHLSSVEVYNIRTDYW 200

  Fly   552 DMVAPIQIARSALSLTPLDEKLYAIGGFDGNNFLSIVEVYDPRTNTWTTGTPLKSGR 608
            ..||.:...|..:..|.|..:||||.|:|||:.||.:|.|||..::|...|.:.:.|
Zfish   201 TTVANMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPVIDSWEVVTSMATQR 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Keap1NP_732202.2 BTB 80..183 CDD:279045
PHA03098 92..599 CDD:222983 89/241 (37%)
BACK 192..294 CDD:285009
Kelch 335..379 CDD:128874 3/14 (21%)
KELCH repeat 369..416 CDD:276965 10/53 (19%)
Kelch 382..430 CDD:128874 12/54 (22%)
KELCH repeat 420..463 CDD:276965 13/42 (31%)
Kelch 433..476 CDD:128874 17/42 (40%)
KELCH repeat 467..510 CDD:276965 18/42 (43%)
Kelch 478..523 CDD:128874 21/44 (48%)
KELCH repeat 514..558 CDD:276965 26/43 (60%)
Kelch_1 514..556 CDD:279660 25/41 (61%)
KELCH repeat 561..606 CDD:276965 19/44 (43%)
Kelch 572..616 CDD:128874 17/37 (46%)
LOC108178999XP_017212974.2 BTB <4..205 CDD:333434 71/198 (36%)
KELCH repeat 19..65 CDD:276965 10/53 (19%)
KELCH repeat 69..112 CDD:276965 13/42 (31%)
KELCH repeat 116..159 CDD:276965 18/42 (43%)
KELCH repeat 163..207 CDD:276965 26/43 (60%)
KELCH repeat 210..255 CDD:276965 19/44 (43%)
Kelch 221..265 CDD:128874 17/37 (46%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D312716at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X9
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.920

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