Protein Alignment Keap1 and LOC100334314

DIOPT Version :10

• Sequence 1: NP_732202.2
• Gene: Keap1 / 42062
• FlyBaseID: FBgn0038475
• Length: 776
• Species: Drosophila melanogaster
• Sequence 2: XP_073784205.1
• Gene: LOC100334314 / 100334314
• -ID: -
• Length: 855
• Species: Danio rerio
• Alignment Length: 682
• Identity: 174/682 - (25%)
• Similarity: 279/682 - (40%)
• Gaps: 97/682 - (14%)

  Fly    12 ETHISDMPNHKGYPCRPEE--AEMSNTSESCSISCGG------------RFGSAH---------- 52
            :|....:|.|...|.:|.:  :.|....:|.:::.||            ..|:.|
Zfish   187 QTPHPQLPAHFQLPQQPSQPMSSMVLNVQSQTLAVGGLPPMPSVCQVAHPVGNGHLTHPMVQSAA 251

  Fly    53 ---STLDDHDATDDDMTFCMSN-------------------YAKEALKMMYMMRSHGMLTDVVLE 95
               |||..:....:.:....||                   :.||.||.:...|.....||:.:.
Zfish   252 LTCSTLPTNGPLANGLQETCSNGLQMLKTVGLGKYEFTDPCHPKEMLKELNQQRREKEFTDLKII 316

  Fly    96 VKKELFPAHKVVLSAASPYFKAM---FTGGLKESEMSRVQLQGVCPTAMSRILYFMYTGQIRVTE 157
            |:.:.|..|:.||::.|.|||.|   .:...:..|..::.:..:....:..:|.|:|||.:.:..
Zfish   317 VEGKEFEVHQNVLASCSLYFKDMVKRLSAENRSGEKMQLSMSNISSDVLELLLEFVYTGSLIIDS 381

  Fly   158 VTVCQLLPAATMFQVPNVIDACCAFLERQLDPTNAIGIAHFAEQHGCVELQKKANVFIERNFTQV 222
            |....||.||..||.......|.:|||:||...|.:|:...||...|.||...|..|..:||..|
Zfish   382 VNAKTLLEAANKFQFSTFCKVCISFLEKQLTAANCLGVLAMAEAMQCTELHNMAKAFALQNFPDV 446

  Fly   223 CQEEEFLQLSAYQLIALIRRDELNVQEEREVYNAVLKWVKYDEDNRHCKMEHILGAVRCQFLTPN 287
            ..:||.|.:|...|::.:..|.||.:.|..||..|:||:|.:..:|...:..:|..||..|:.|:
Zfish   447 AGQEEILNVSKEDLVSYMSNDSLNTKAEELVYETVIKWIKKEPSSRVQHVSELLAVVRLPFIHPS 511

  Fly   288 FLKEQMKNCDVLRKVPACREYL--AKIFKDLTLHKCPGVKE--RTPNTTR---------MIFVAG 339
            :|...:.|.::::...|||:.:  ||.:     |..|..::  :||.|..         ::.|.|
Zfish   512 YLLNVVDNEELIKSSEACRDLVNEAKRY-----HMLPHARQEMQTPRTRPRLSAGVAEVIVLVGG 571

  Fly   340 ----GFFRHSLDILEAYNVDDMTWTTLANLRIPRSGLGAAFLKGKFYAVGGRNNNI--------G 392
                |....||..:..:|..:..|..||:|         .|...:|::|....:||        |
Zfish   572 RQVVGMNHRSLTAVTCFNPQNNKWYPLASL---------PFYNREFFSVVSAGDNIYLSGGVESG 627

  Fly   393 SSYDSDWVDRYSAVTETWRPCAPMSVPRHRVGVAVMDELMYAVGGSAGMEYHNTVEYYDPDLDRW 457
            .:....|.  |.::.:.|...:.|:|.|.|....|.|..:||:||.......:.||.||...::|
Zfish   628 VTLADVWC--YMSLLDNWNLVSRMTVSRCRHNSVVYDGKLYAIGGLGAAGNLDNVERYDTITNQW 690

  Fly   458 TLVQPMHAKRLGVGVVVVNRLLYAIGGFDGNERLASV-ECYHPENNEWSFLPPLQTGRSGAGVAA 521
            .:|.|:..........|....:|..||.:...|.|.| :.|.|:.|.|||:.........|....
Zfish   691 EMVAPLPKPVHSAAATVCGGKIYVFGGVNEAGRSAGVLQSYVPQTNAWSFIESPMIDNKYAPAVT 755

  Fly   522 INQYIYVVGGFDGTRQLATVERYDTENDTWDMVAPIQIARSALSLTPLDEKLYAIGGFDGNN--F 584
            :|.||:::||  ...:..|:  ||.|.........:..:|...|...||.|::|.||...:.  .
Zfish   756 LNGYIFILGG--AYARATTI--YDPEKGNIKAGPNMNHSRQFCSAVVLDGKIFASGGIVSSEGPA 816

  Fly   585 LSIVEVYDPRTNTWTTGTPLKSGRSGHASAVI 616
            |..:|..||..|.||....:......|...||
Zfish   817 LGTMEALDPCANVWTLQQSMPCPLFRHGCVVI 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Keap1	NP_732202.2	PHA03098	92..599	CDD:222983	146/537 (27%)
		KELCH repeat	369..416	CDD:276965	9/54 (17%)
		KELCH repeat	420..463	CDD:276965	14/42 (33%)
		KELCH repeat	467..510	CDD:276965	13/43 (30%)
		KELCH repeat	514..558	CDD:276965	10/43 (23%)
		KELCH repeat	561..606	CDD:276965	15/46 (33%)
LOC100334314	XP_073784205.1	None