DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS11 and MRPS11

DIOPT Version :9

Sequence 1:	NP_524382.1	Gene:	mRpS11 / 42061	FlyBaseID:	FBgn0038474	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_073750.2	Gene:	MRPS11 / 64963	HGNCID:	14050	Length:	194	Species:	Homo sapiens

Alignment Length:	202	Identity:	77/202 - (38%)
Similarity:	106/202 - (52%)	Gaps:	25/202 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 MPAVPLQTSRIHTSACWRKAEDRKEMLASLPAKDEGTV--GEKTVDIDTLINRKAKFFPDASTAN 78
            |.||....||...|..|.:...|  ::|..||   ||:  |.:.:. |....:|.:  .:|:.::
Human     1 MQAVRNAGSRFLRSWTWPQTAGR--VVARTPA---GTICTGARQLQ-DAAAKQKVE--QNAAPSH 57

  Fly    79 TLFN---------------GIPFNELPICNIRVSPNNTIISVTDHKGVLRLIRSCGIEGFKNTRK 128
            |.|:               |..|.|:||.:|:.|.|||.|.|...........|||.|||:|.:|
Human    58 TKFSIYPPIPGEESSLRWAGKKFEEIPIAHIKASHNNTQIQVVSASNEPLAFASCGTEGFRNAKK 122

  Fly   129 GTNIAAQATAVTISGKAIELGWKTVRVKVRGLGPGRMSAIKGLQMGGLNIVSITDNTHVSFNPPR 193
            ||.||||...:..:.:|.:.|...:||.|:||||||:||:.||.||||.::||||||.:..|..|
Human   123 GTGIAAQTAGIAAAARAKQKGVIHIRVVVKGLGPGRLSAMHGLIMGGLEVISITDNTPIPHNGCR 187

  Fly   194 PRKQRSL 200
            |||.|.|
Human   188 PRKARKL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS11	NP_524382.1	Ribosomal_S11	91..198	CDD:294237	52/106 (49%)
MRPS11	NP_073750.2	PRK02812	<30..104	CDD:235072	21/79 (27%)
MRPS11	NP_073750.2	Ribosomal_S11	85..193	CDD:320911	52/107 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143225
Domainoid	1	1.000	103	1.000	Domainoid score	I6800
eggNOG	1	0.900	-	-		E1_COG0100
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4853
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1303296at2759
OrthoFinder	1	1.000	-	-		FOG0004727
OrthoInspector	1	1.000	-	-		oto91723
orthoMCL	1	0.900	-	-		OOG6_100266
Panther	1	1.100	-	-	LDO	PTHR11759
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3942
SonicParanoid	1	1.000	-	-		X3323
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790