DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ns1 and der

DIOPT Version :9

Sequence 1:	NP_732199.2	Gene:	Ns1 / 42060	FlyBaseID:	FBgn0038473	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_417006.2	Gene:	der / 946983	ECOCYCID:	G7319	Length:	490	Species:	Escherichia coli

Alignment Length:	290	Identity:	69/290 - (23%)
Similarity:	111/290 - (38%)	Gaps:	52/290 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 EQSLKQYFKEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKAD-LVPRE 197
            ||||        ..||.|||||.:||||..|......:.:.:|..  .|...||.||.| |.|.:
E. coli    73 EQSL--------LAIEEADVVLFMVDARAGLMPADEAIAKHLRSR--EKPTFLVANKTDGLDPDQ 127

  Fly   198 NLNNWIKYFRRSGPVTAFKASTQDQANRLGRRKLREMKTEKAMQGSVCIGAELLMSMLGNYCRNK 262
            .:.::  |....|.:....||.......|....|.....:.|.|..|...||.....   .....
E. coli   128 AVVDF--YSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQF---EAEEN 187

  Fly   263 GIKTS----------IRVGVVGIPNVGKSSIINSLTRGRSCMVGSTPGVTKSMQEVELD---SKI 314
            |.:..          |::.:||.||||||::.|.:......:|...||.|:....:.::   .:.
E. coli   188 GEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREY 252

  Fly   315 KLIDCPGIVFTSGGENSHAVLKNAQRVGDVKDPFTIAESVLKRASKEYFCTMYDITNYDTFEEFF 379
            .|||..|:             :...::.|..:.|::.:::  :|.::....|..|   |..|...
E. coli   253 VLIDTAGV-------------RKRGKITDAVEKFSVIKTL--QAIEDANVVMLVI---DAREGIS 299

  Fly   380 AKKAARMGKFLKKGVPDVVAAARSVLNDWN 409
            .:..:.:|..|..|...|:     |:|.|:
E. coli   300 DQDLSLLGFILNSGRSLVI-----VVNKWD 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863
		SurA_N_3	59..>150	CDD:304439	5/15 (33%)
		RbgA	121..443	CDD:224083	69/290 (24%)
		Nucleostemin_like	152..322	CDD:206753	47/183 (26%)
		Ras_like_GTPase	271..>400	CDD:206648	28/131 (21%)
der	NP_417006.2	PRK00093	3..462	CDD:234628	69/290 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I753
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	1	1.000