DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ns1 and MTG1

DIOPT Version :9

Sequence 1:	NP_732199.2	Gene:	Ns1 / 42060	FlyBaseID:	FBgn0038473	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_612393.2	Gene:	MTG1 / 92170	HGNCID:	32159	Length:	334	Species:	Homo sapiens

Alignment Length:	298	Identity:	81/298 - (27%)
Similarity:	129/298 - (43%)	Gaps:	53/298 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 KEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPRENLNNWIKYF 206
            |:.:..::..|.::||.|||.||..|....:..:    |.|..:|||||.||.........:::.
Human    40 KKMQSSLKLVDCIIEVHDARIPLSGRNPLFQETL----GLKPHLLVLNKMDLADLTEQQKIMQHL 100

  Fly   207 RRSG-PVTAFKASTQDQANRLGRRKLREMKTEKAMQGSVCIGAELLMSMLGNYCRNKGIKTSIRV 270
            ...| ....|....:|:    ..:::..|.||             |:.....|.|.:.::..|.
Human   101 EGEGLKNVIFTNCVKDE----NVKQIIPMVTE-------------LIGRSHRYHRKENLEYCIM- 147

  Fly   271 GVVGIPNVGKSSIINSLTR-----GRSCMVGSTPGVTKS-MQEVELDSK--IKLIDCPGIVFTSG 327
             |:|:|||||||:||||.|     |::..||..||:|:: |.::::..:  :.|:|.|| |....
Human   148 -VIGVPNVGKSSLINSLRRQHLRKGKATRVGGEPGITRAVMSKIQVSERPLMFLLDTPG-VLAPR 210

  Fly   328 GENSHAVLKNAQRVGDVKDPF----TIAESVLKRASKEY---FCTMYDI-TNYDTFEEFFAKKAA 384
            .|:....||.| ..|.|.|..    |:|:.:|...:|..   :...|.: :..|..|......|.
Human   211 IESVETGLKLA-LCGTVLDHLVGEETMADYLLYTLNKHQRFGYVQHYGLGSACDNVERVLKSVAV 274

  Fly   385 RMGKFLKKGV-----------PDVVAAARSVLNDWNTG 411
            ::||..|..|           |:..||||..|..:..|
Human   275 KLGKTQKVKVLTGTGNVNIIQPNYPAAARDFLQTFRRG 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863
		SurA_N_3	59..>150	CDD:304439	1/7 (14%)
		RbgA	121..443	CDD:224083	81/298 (27%)
		Nucleostemin_like	152..322	CDD:206753	52/178 (29%)
		Ras_like_GTPase	271..>400	CDD:206648	46/155 (30%)
MTG1	NP_612393.2	GTPase_YlqF	30..320	CDD:274669	81/298 (27%)
MTG1	NP_612393.2	YlqF	30..207	CDD:206749	54/190 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810